(Q48488443)

English

Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils.

scientific article published in May 1998

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scholarly article

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/9547230

Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792661&resulttype=core&format=json

12 May 2020

Alzheimer's disease

0 references

1 reference

based on heuristic

inferred from title

toxic encephalopathy

1 reference

based on heuristic

inferred from title

author name string

A Alvarez

1

1 reference

Europe PubMed Central

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12 May 2020

R Alarcón

2

1 reference

Europe PubMed Central

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12 May 2020

C Opazo

3

1 reference

Europe PubMed Central

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12 May 2020

E O Campos

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792661&resulttype=core&format=json

12 May 2020

F J Muñoz

5

1 reference

Europe PubMed Central

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12 May 2020

F H Calderón

6

1 reference

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12 May 2020

F Dajas

7

1 reference

Europe PubMed Central

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12 May 2020

M K Gentry

8

1 reference

Europe PubMed Central

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12 May 2020

B P Doctor

9

1 reference

Europe PubMed Central

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12 May 2020

F G De Mello

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792661&resulttype=core&format=json

12 May 2020

N C Inestrosa

11

1 reference

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12 May 2020

language of work or name

0 references

publication date

1 May 1998

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/9547230

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792661&resulttype=core&format=json

12 May 2020

18

1 reference

Europe PubMed Central

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12 May 2020

9

1 reference

Europe PubMed Central

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12 May 2020

3213-3223

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792661&resulttype=core&format=json

12 May 2020

The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fasciculins, anticholinesterase toxins from the venom of the green mamba Dendroaspis angusticeps.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of sickle hemoglobin polymerization. II. A double nucleation mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxic effects of acetylcholinesterase on neuronal and glial-like cells in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and cellular biology of cholinesterases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution and anchoring of molecular forms of acetylcholinesterase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the peripheral anionic site on acetylcholinesterase: inhibition by substrates and coumarin derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two simple methods for quantifying low-affinity dye-substrate binding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive substrate inhibition in the histochemistry of cholinesterase activity in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E carboxyl-terminal fragments are complexed to amyloids A and L. Implications for amyloidogenesis and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic analysis of amyloid fibril polymerization in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructural localization of acetylcholinesterase in neurofibrillary tangles, neuropil threads and senile plaques in aged and Alzheimer's brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electron microscopic analysis of aggregation of embryonic cells: the structure and differentiation of aggregates of neural retina cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities of acetylcholinesterase in Alzheimer's disease with special reference to effect of acetylcholinesterase inhibitor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

About the presence of paired helical filaments in dystrophic neurites participating in the plaque formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Butyrylcholinesterase reactivity differentiates the amyloid plaques of aging from those of dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of dopamine agonist and antagonist binding sites in mammalian retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of apolipoprotein E on neurite outgrowth and beta-amyloid-induced toxicity in developing rat primary hippocampal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholinesterase and its association with heparan sulphate proteoglycans in cortical amyloid deposits of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of neuronal degeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-classical actions of cholinesterases: role in cellular differentiation, tumorigenesis and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholinesterase is a senile plaque component that promotes assembly of amyloid beta-peptide into Alzheimer's filaments.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholinesterase provides deeper insights into Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholinesterase, a senile plaque component, affects the fibrillogenesis of amyloid-beta-peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular localization of the molecular forms of acetylcholinesterase in rat pheochromocytoma PC12 cells treated with nerve growth factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senile plaques: staining for acetylcholinesterase and A4 protein: a comparative study in the hippocampus and entorhinal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clusterin (apoJ) alters the aggregation of amyloid beta-peptide (A beta 1-42) and forms slowly sedimenting A beta complexes that cause oxidative stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic acetylcholine receptors of the developing retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gamma-aminobutyric acid (GABA) receptor binding in mammalian retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electron microscopic localization of cholinesterase activity in Alzheimer brain tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of acetylcholine receptors during synaptogenesis in retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification, ultrastructure, and chemical analysis of Alzheimer disease amyloid plaque core protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new and rapid colorimetric determination of acetylcholinesterase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease inhibitors and indoleamines selectively inhibit cholinesterases in the histopathologic structures of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine-Elicited Accumulation of Adenosine 3', 5'-Cyclic Monophosphate in the Chick Embryo Retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colocalization of cholinesterases with beta amyloid protein in aged and Alzheimer's brains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat striatal acetylcholinesterase inhibition by fasciculin (a polypeptide from green mamba snake venom)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of acetylcholinesterase with the cell surface

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fasciculin, a powerful anticholinesterase polypeptide from Dendroaspis angusticeps venom

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrolysis of suxamethonium by different types of plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of normal and pathological aging in prospectively studied nondemented elderly humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new solid-state reagent to iodinate proteins. I. Conditions for the efficient labeling of antiserum

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surfactant properties of Alzheimer's A beta peptides and the mechanism of amyloid aggregation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clusterin (Apo J) protects against in vitro amyloid-beta (1-40) neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anatomy of cholinesterase inhibition in Alzheimer's disease: effect of physostigmine and tetrahydroaminoacridine on plaques and tangles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of monoclonal antibodies that inhibit the catalytic activity of acetylcholinesterases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ORNITHINE AND GLUTAMIC ACID DECARBOXYLASE ACTIVITIES IN THE DEVELOPING CHICK RETINA

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural determinants of the Alzheimer's amyloid beta-peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation state and neurotoxic properties of Alzheimer beta-amyloid peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cholinesterases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular distribution of acetylcholinesterase in Alzheimer's disease: abnormal localization and solubilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: genotypes, phenotypes, and treatments

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholinesterase from bovine caudate nucleus is attached to membranes by a novel subunit distinct from those of acetylcholinesterases in other tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methodological variables in the assessment of beta amyloid neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synapse turnover: the formation and termination of transient synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cholinergic system in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synapse and acetylcholine receptor synthesis by neurons dissociated from retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.18-09-03213.1998

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792661&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792661&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792661&resulttype=core&format=json

12 May 2020

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