(Q48510557)

12 February 2018

title

Aryl and cycloalkyl analogues of AMPA: synthetic, pharmacological and stereochemical aspects (English)

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12 February 2018

author name string

Skjaerbaek N

1

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12 February 2018

Brehm L

2

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12 February 2018

Johansen TN

3

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12 February 2018

Hansen LM

4

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12 February 2018

Nielsen B

5

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12 February 2018

Ebert B

6

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12 February 2018

Søby KK

7

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12 February 2018

Stensbøl TB

8

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12 February 2018

Falch E

9

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12 February 2018

Krogsgaard-Larsen P

10

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12 February 2018

language of work or name

English

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publication date

1 January 1998

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12 February 2018

Bioorganic & Medicinal Chemistry

published in

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12 February 2018

volume

6

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12 February 2018

issue

1

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12 February 2018

page(s)

119-131

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12 February 2018

Metabotropic glutamate receptors: novel targets for drug development

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Treatment of Alzheimer's disease. Molecular pathology versus neurotransmitter-based therapy

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Modulation of AMPA receptor function in relation to glutamatergic abnormalities in Alzheimer's disease

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Excitatory amino acid receptors in schizophrenia

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Structural, conformational, and stereochemical requirements of central excitatory amino acid receptors

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Design of excitatory amino acid receptor agonists, partial agonists and antagonists: ibotenic acid as a key lead structure

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Comparison of L-[3H]glutamate, D-[3H]aspartate, DL-[3H]AP5 and [3H]NMDA as ligands for NMDA receptors in crude postsynaptic densities from rat brain

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Glycine is a coagonist at the NMDA receptor/channel complex

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Cooperative modulation of [3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine, and polyamines

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Inhibition of [3H]kainic acid receptor binding by divalent cations correlates with ion affinity for the calcium channel

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Non-NMDA glutamate receptor antagonist 3H-CNOX binds with equal affinity to two agonist states of quisqualate receptors

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Resolution, absolute stereochemistry, and pharmacology of the S-(+)- and R-(-)-isomers of the apparent partial AMPA receptor agonist (R,S)-2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid [(R,S)-APPA].

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Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA.

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Functional partial agonism at ionotropic excitatory amino acid receptors

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AMPA receptor agonists: resolution, configurational assignment, and pharmacology of (+)-(S)- and (-)-(R)-2-amino-3-[3-hydroxy-5-(2-pyridyl)-isoxazol-4-yl]-propionic acid (2-Py-AMPA).

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Partial GABAA Receptor Agonists. Synthesis and in Vitro Pharmacology of a Series of Nonannulated Analogs of 4,5,6,7-Tetrahydroisoxazolo[4,5-c]pyridin-3-ol

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7 January 2021

Chromatographic separation of racemic amino acids by use of chiral crown ether-coated reversed-phase packings

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7 January 2021

Estimation of antagonist Kb from inhibition curves in functional experiments: alternatives to the Cheng-Prusoff equation.

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7 January 2021

Heteroaryl analogues of AMPA. Synthesis and quantitative structure-activity relationships

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7 January 2021

Desiccant efficiency in solvent drying. 3. Dipolar aprotic solvents

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7 January 2021

Rapid chromatographic technique for preparative separations with moderate resolution

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7 January 2021

Structure-activity relationships in 1,4-benzodioxan-related compounds. 4. Effect of aryl and alkyl substituents at position 3 on alpha-adrenoreceptor blocking activity

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The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain

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Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex

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7 January 2021

10.1016/S0968-0896(97)10017-7

Identifiers

DOI

1 reference

12 February 2018

1 reference

12 February 2018