(Q48541286)

12 February 2018

title

PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells. (English)

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12 February 2018

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Jose C. Perales

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12 February 2018

author name string

Calvo MN

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12 February 2018

Castaño E

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Navarro-Sabaté A

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12 February 2018

Manzano A

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language of work or name

English

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publication date

8 May 2006

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12 February 2018

published in

FEBS Letters

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12 February 2018

volume

580

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12 February 2018

page(s)

3308-3314

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12 February 2018

issue

13

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12 February 2018

On the Origin of Cancer Cells

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An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect

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Fructose 2,6-bisphosphate and the control of glycolysis by growth factors, tumor promoters and oncogenes

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6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

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PFK-2/FBPase-2: maker and breaker of the essential biofactor fructose-2,6-bisphosphate.

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6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia

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Recently elucidated energy catabolism pathways provide opportunities for novel treatments in hepatocellular carcinoma

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A unique glucose-dependent apoptotic pathway induced by c-Myc

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Analysis of gene function in somatic mammalian cells using small interfering RNAs

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“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

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Insulin induces PFKFB3 gene expression in HT29 human colon adenocarcinoma cells

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Specific expression of pfkfb4 gene in spermatogonia germ cells and analysis of its 5'-flanking region.

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Knockdown by RNAi-proceed with caution.

21 January 2018

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No induction of anti-viral responses in human cell lines HeLa and MCF-7 when transfecting with siRNA or siLNA.

21 January 2018

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Control of fructose 2,6-bisphosphate metabolism by different mitogenic signals in Swiss 3T3 fibroblasts

21 January 2018

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Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death

21 January 2018

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21 January 2018

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2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo

21 January 2018

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Cells overexpressing fructose-2,6-bisphosphatase showed enhanced pentose phosphate pathway flux and resistance to oxidative stress

21 January 2018

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21 January 2018

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21 January 2018

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14-3-3s regulate fructose-2,6-bisphosphate levels by binding to PKB-phosphorylated cardiac fructose-2,6-bisphosphate kinase/phosphatase

21 January 2018

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Survival-promoting functions of 14-3-3 proteins

21 January 2018

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Multifaceted roles of glycolytic enzymes.

21 January 2018

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Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.04.093

10.1016/J.FEBSLET.2006.04.093

21 January 2018

Identifiers

DOI

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12 February 2018

PubMed ID

16698023

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12 February 2018