(Q48545940)

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Leptin regulates growth hormone-releasing factor, somatostatin, and alpha-melanocyte-stimulating hormone but not neuropeptide Y release in rat hypothalamus in vivo: relation with growth hormone secretion.

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/12122085

Leptin regulates growth hormone-releasing factor, somatostatin, and alpha-melanocyte-stimulating hormone but not neuropeptide Y release in rat hypothalamus in vivo: relation with growth hormone secretion (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757925&resulttype=core&format=json

12 May 2020

author name string

Hajime Watanobe

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757925&resulttype=core&format=json

12 May 2020

Satoshi Habu

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757925&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 July 2002

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/12122085

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757925&resulttype=core&format=json

12 May 2020

22

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757925&resulttype=core&format=json

12 May 2020

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757925&resulttype=core&format=json

12 May 2020

6265-6271

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757925&resulttype=core&format=json

12 May 2020

Interacting appetite-regulating pathways in the hypothalamic regulation of body weight

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central administration of leptin to ovariectomized ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland: evidence for a dissociation of effects on appetite and neuroendocrine function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin binding in the arcuate nucleus is increased during fasting

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A detailed study on the role of sex steroid milieu in determining plasma leptin concentrations in adult male and female rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin regulates GH secretion in the rat by acting on GHRH and somatostatinergic functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human growth hormone-releasing hormone transgenic mouse as a model of modest obesity: differential changes in leptin receptor (OBR) gene expression in the anterior pituitary and hypothalamus after fasting and OBR localization in somatotrophs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin and leptin receptor expression in normal and neoplastic human pituitary: evidence of a regulatory role for leptin on pituitary cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroendocrine regulation and actions of leptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin and leptin receptor expression in rat and mouse pituitary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin increases in vivo GH responses to GHRH and GH-releasing peptide-6 in food-deprived rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of neuropeptide Y release from hypothalamic slices by melanocortin-4 agonists and leptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroendocrine consequences of fasting in adult male macaques: effects of recombinant rhesus macaque leptin infusion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of leptin receptor-like immunoreactivity in the corticotropes, somatotropes, and gonadotropes in the ovine anterior pituitary

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin regulation of neuroendocrine systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long form leptin receptor mRNA expression in the brain, pituitary, and other tissues in the pig.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin rapidly inhibits hypothalamic neuropeptide Y secretion and stimulates corticotropin-releasing hormone secretion in adrenalectomized mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin regulates pulsatile luteinizing hormone and growth hormone secretion in the sheep.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of long-form leptin receptor in the somatostatin-containing neurons in the sheep hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of prolactin secretion by chronic, but not acute, administration of leptin in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebroventricular infusion of leptin elevates the secretion of luteinising hormone without affecting food intake in long-term food-restricted sheep, but increases growth hormone irrespective of bodyweight

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central infusion of leptin into well-fed and undernourished ewe lambs: effects on feed intake and serum concentrations of growth hormone and luteinizing hormone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The in vitro effect of leptin on growth hormone secretion from primary cultured ovine somatotrophs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normalization of circulating leptin levels by fasting improves the reproductive function in obese OLETF female rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central melanocortin receptors mediate changes in food intake in the rhesus macaque

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The release of leptin and its effect on hormone release from human pituitary adenomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct modification of somatotrope function by long-term leptin treatment of primary cultured ovine pituitary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of metabolic substrates and obesity on growth hormone secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of food deprivation in the rat on hypothalamic expression of growth hormone-releasing factor and somatostatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiology of the somatotropic axis with particular reference to the ruminant

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Entry of peroxidase into neurons of the central and peripheral nervous systems from extracerebral and cerebral blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of neuropeptide Y in the antiobesity action of the obese gene product

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical mapping of neuropeptides in the premamillary region of the hypothalamus in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of intravenous administration of interleukin-1-beta on the release of prostaglandin E2, corticotropin-releasing factor, and arginine vasopressin in several hypothalamic areas of freely moving rats: estimation by push-pull perfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutritional regulation of the insulin-like growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo release of neurotensin from the median eminence of ovariectomized estrogen-primed rats as estimated by push-pull perfusion: correlation with luteinizing hormone and prolactin surges

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrahypothalamic perfusion with interleukin-1-beta stimulates the local release of corticotropin-releasing hormone and arginine vasopressin and the plasma adrenocorticotropin in freely moving rats: a comparative perfusion of the paraventricular nuc

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of targets of leptin action in rat hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of in vivo growth hormone secretion by leptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatostatin release as measured by in vivo microdialysis: circadian variation and effect of prolonged food deprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine function of neuropeptide Y knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin inhibits in vitro hypothalamic somatostatin secretion and somatostatin mRNA levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant porcine leptin reduces feed intake and stimulates growth hormone secretion in swine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of fasting and leptin deficiency on hypothalamic neuropeptide Y gene transcription in vivo revealed by expression of a lacZ reporter gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orchiectomy and response to testosterone in the development of obesity in young Otsuka-Long-Evans-Tokushima Fatty (OLETF) rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distributions of leptin receptor mRNA isoforms in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a leptin-neuropeptide Y axis for the regulation of growth hormone secretion in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin is a potent stimulator of spontaneous pulsatile growth hormone (GH) secretion and the GH response to GH-releasing hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between leptin and neuropeptide Y on in vivo growth hormone secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stimulatory effect of leptin on the neuroendocrine reproductive axis of the monkey

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin alters the response of the growth hormone releasing factor- growth hormone--insulin-like growth factor-I axis to fasting

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intact leptin receptor is selectively expressed in human fetal pituitary and pituitary adenomas and signals human fetal pituitary growth hormone secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The in vitro effect of leptin on basal and growth hormone-releasing hormone-stimulated growth hormone secretion from the ovine pituitary gland.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin activates hypothalamic CART neurons projecting to the spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of growth hormone (GH)-releasing hormone and somatostatin on leptin-induced GH secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12122085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.22-14-06265.2002

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757925&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757925&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757925&resulttype=core&format=json

12 May 2020

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