(Q48546243)

12 February 2018

title

'Gimme five': future challenges in multiple sclerosis. ECTRIMS Lecture 2009. (English)

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12 February 2018

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Reinhard Hohlfeld

1

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12 February 2018

publication date

9 December 2009

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12 February 2018

Multiple Sclerosis Journal

published in

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12 February 2018

volume

16

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12 February 2018

issue

1

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12 February 2018

page(s)

3-14

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12 February 2018

Ethics of placebo-controlled clinical trials in multiple sclerosis: a reassessment

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Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.

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EAE: an immunologist's magic eye.

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The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

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Gene transfer into CD4+ T lymphocytes: green fluorescent protein-engineered, encephalitogenic T cells illuminate brain autoimmune responses

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In vivo imaging of the diseased nervous system

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Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells.

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Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

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Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.

21 January 2018

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The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease

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Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity.

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T-cell-mediated autoimmunity: novel techniques to characterize autoreactive T-cell receptors

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Multiple sclerosis: T-cell receptor expression in distinct brain regions

21 January 2018

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21 January 2018

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21 January 2018

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Axonal transection in the lesions of multiple sclerosis

21 January 2018

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Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time

21 January 2018

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The relation between inflammation and neurodegeneration in multiple sclerosis brains.

21 January 2018

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Dual role of inflammation in CNS disease

21 January 2018

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Neurotrophic cross-talk between the nervous and immune systems: implications for neurological diseases

21 January 2018

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Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?

21 January 2018

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Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss

21 January 2018

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Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

21 January 2018

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The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases

21 January 2018

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Neurofascin as a novel target for autoantibody-mediated axonal injury

21 January 2018

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Development of biomarkers in multiple sclerosis

21 January 2018

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A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis

21 January 2018

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Neuromyelitis optica: pathogenicity of patient immunoglobulin in vivo.

21 January 2018

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Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica

21 January 2018

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Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score

21 January 2018

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21 January 2018

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Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

21 January 2018

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Late-onset tumor necrosis factor receptor-associated periodic syndrome in multiple sclerosis patients carrying the TNFRSF1A R92Q mutation

21 January 2018

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Multiple sclerosis and the TNFRSF1A R92Q mutation: clinical characteristics of 21 cases

21 January 2018

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Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/1352458509357355

1 reference

12 February 2018

1 reference

12 February 2018