(Q48559543)

English

Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata

scientific article published in October 1997

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

Alzheimer's disease

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Elizabeth J. Coulson

1

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

author name string

Barrett GL

2

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

Storey E

3

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

Bartlett PF

4

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

Beyreuther K

5

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

Masters CL

6

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

language of work or name

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publication date

1 October 1997

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

number of pages

9

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based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

770

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

1-2

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

72-80

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro

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Trophic effect of beta-amyloid precursor protein on cerebral cortical neurons in culture

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The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development

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Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I.

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7 January 2021

Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion

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7 January 2021

APP-collagen interaction is mediated by a heparin bridge mechanism.

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Synapse formation occurs in association with the induction of long-term potentiation in two-year-old rat hippocampus in vitro

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An antibody to beta amyloid and the amyloid precursor protein inhibits cell-substratum adhesion in many mammalian cell types

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7 January 2021

Integral membrane heparan sulfate proteoglycans

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Alzheimer's disease amyloid precursor protein (ApPP): proteolytic processing, secretases and βA4 amyloid production

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Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.

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Alzheimer's disease amyloid precursor protein is present in senile plaques and cerebrospinal fluid: immunohistochemical and biochemical characterization.

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7 January 2021

A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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Expression of beta amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR.

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A heparan sulfate proteoglycan in developing avian axonal tracts

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Probing the function of novel genes in the nervous system: is antisense the answer?

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7 January 2021

Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension

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Localization of a laminin-binding protein in brain

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Plasticity of sensory and motor maps in adult mammals

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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beta-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin

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7 January 2021

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

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Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

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Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowth

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Role of amyloid precursor protein (APP): study with antisense transfection of human neuroblastoma cells

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beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

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7 January 2021

Secreted forms of beta-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons

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7 January 2021

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth

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Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain

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7 January 2021

Interaction between the zinc (II) and the heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP).

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7 January 2021

Transforming growth factor beta mediates increase of mature transmembrane amyloid precursor protein in microglial cells

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Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene

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Developmental regulation of neural response to FGF-1 and FGF-2 by heparan sulfate proteoglycan.

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Developmental and differential expression of beta amyloid protein precursor mRNAs in mouse brain

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The chondroitin sulfate attachment site of appican is formed by splicing out exon 15 of the amyloid precursor gene

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A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

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Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner

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Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.

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Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate

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The expression of amyloid beta protein precursor protects nerve cells from beta-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix

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Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

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Association and release of the amyloid protein precursor of Alzheimer's disease from chick brain extracellular matrix

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A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth

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Platelet coagulation factor XIa-inhibitor, a form of Alzheimer amyloid precursor protein

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Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components

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The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites.

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Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

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Distribution of an APP homolog, APLP2, in the mouse olfactory system: a potential role for APLP2 in axogenesis.

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Extracellular matrix. 2: Role of extracellular matrix molecules and their receptors in the nervous system.

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Gene inhibition using antisense oligodeoxynucleotides

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Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

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Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

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Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

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Specificity of antisense oligonucleotides in vivo

1 reference

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Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons

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Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells

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Laminin--developmental expression and role in axonal outgrowth in the peripheral nervous system of the chick

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Identifiers

10.1016/S0006-8993(97)00757-9

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9372205

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