(Q48561566)

12 February 2018

title

MPTP produces differential oxidative stress and antioxidative responses in the nigrostriatal and mesolimbic dopaminergic pathways. (English)

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12 February 2018

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Hung HC

1

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12 February 2018

Lee EH

series ordinal

2

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12 February 2018

publication date

1 January 1998

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12 February 2018

Free Radical Biology and Medicine

published in

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12 February 2018

volume

24

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12 February 2018

issue

1

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12 February 2018

page(s)

76-84

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12 February 2018

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

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A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

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Hydrogen peroxide production by monoamine oxidase in isolated rat-brain mitochondria: its effect on glutathione levels and Ca2+ efflux

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7 January 2021

Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: effects of MPP+

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7 January 2021

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

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7 January 2021

MPP+ and MPDP+ induced oxygen radical formation with mitochondrial enzymes.

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7 January 2021

Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement

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7 January 2021

Central catecholamine neuron systems: anatomy and physiology of the dopamine systems

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7 January 2021

Parkinson's disease: loss of neurons from the ventral tegmental area contralateral to therapeutic surgical lesions

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7 January 2021

Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease

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7 January 2021

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian syndrome in Macaca fascicularis: which midbrain dopaminergic neurons are lost?

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An immunohistochemical study of the acute and long-term effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the marmoset

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7 January 2021

Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization

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7 January 2021

Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease.

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7 January 2021

1-Methyl-4-phenyl-pyridinium (MPP+) uptake does not explain the differential toxicity of MPP+ in the nigrostriatal and mesolimbic dopaminergic pathways

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7 January 2021

The mesolimbic dopaminergic pathway is more resistant than the nigrostriatal dopaminergic pathway to MPTP and MPP+ toxicity: role of BDNF gene expression.

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7 January 2021

The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective

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7 January 2021

Oxygen radicals as key mediators in neurological disease: fact or fiction?

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7 January 2021

Dynamics of lipid peroxidation and its inhibition by antioxidants

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7 January 2021

Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal

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7 January 2021

Experimental Parkinson's disease in monkeys. Effect of ergot alkaloid derivative on lipid peroxidation in different brain areas

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7 January 2021

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by pretreatment with diethyldithiocarbamate.

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7 January 2021

Induction by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine of lipid peroxidation in vivo in vitamin E deficient mice.

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7 January 2021

Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones.

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7 January 2021

Determination of glutathione and glutathione disulfide in biological samples

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7 January 2021

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7 January 2021

Assays of glutathione peroxidase

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7 January 2021

N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces cytoskeletal alterations on 'Swiss 3T3' mouse fibroblasts

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7 January 2021

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) affects the actin cytoskeleton and calcium level of Swiss 3T3 mouse fibroblasts

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7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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7 January 2021

Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease

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7 January 2021

Parkinson's disease: a disorder due to nigral glutathione deficiency?

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7 January 2021

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

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7 January 2021

A selective increase in particulate superoxide dismutase activity in parkinsonian substantia nigra

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7 January 2021

Increased striatal lipid peroxidation after intracerebroventricular MPP+ administration to mice.

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7 January 2021

Evidence for retrograde axonal transport of MPP+ in the rat.

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7 January 2021

Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on levels of glutathione in the extrapyramidal system of the mouse.

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7 January 2021

Depletion of glutathione in brainstem of mice caused by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant pretreatment.

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7 January 2021

Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons

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7 January 2021

Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain.

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7 January 2021

Induction of manganese superoxide dismutase by cytokines and lipopolysaccharide in cultured mouse astrocytes.

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7 January 2021

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900206-2

7 January 2021

Inhibition of cytotoxicity by intracellular superoxide dismutase supplementation.

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7 January 2021

Induction of copper-zinc superoxide dismutase in gerbil hippocampus after ischemia.

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7 January 2021

Preferential expression of superoxide dismutase messenger RNA in melanized neurons in human mesencephalon.

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7 January 2021

Oxygen toxicity, oxygen radicals, transition metals and disease

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7 January 2021

Relationship of resistance to oxygen free radicals to CuZn‐superoxide dismutase activity in transgenic, transfected, and trisomic cells

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7 January 2021

Superoxide dismutase, glutathione peroxidase and lipoperoxidation in Oown's syndrome fetal brain

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7 January 2021

Evidence against the involvement of reactive oxygen species in the pathogenesis of neuronal death in down's syndrome and Alzheimer's Disease

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7 January 2021

Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome

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7 January 2021

Neuronal-specific expression of human copper-zinc superoxide dismutase gene in transgenic mice: animal model of gene dosage effects in Down's syndrome

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7 January 2021

Increased iron in the substantia nigra compacta of the MPTP-lesioned hemiparkinsonian African green monkey: evidence from proton microprobe elemental microanalysis.

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7 January 2021

On the participation of higher oxidation states of iron and copper in Fenton reactions

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7 January 2021

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Identifiers

DOI

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12 February 2018

PubMed ID

9436616

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12 February 2018