(Q48580864)

13 February 2018

title

Bowman Lecture 1998. Diabetic retinopathy: some cellular, molecular and therapeutic considerations. (English)

1 reference

13 February 2018

1 reference

Archer DB

1

1 reference

13 February 2018

publication date

1 August 1999

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13 February 2018

published in

Eye

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13 February 2018

volume

13 ( Pt 4)

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13 February 2018

page(s)

497-523

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13 February 2018

https://scigraph.springernature.com/pub.10.1038/eye.1999.130

exact match

0 references

cites work

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Selective loss of vascular smooth muscle cells in the retinal microcirculation of diabetic dogs

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Role of glucose regulatory mechanisms in diabetic retinopathy.

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Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor.

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Structure-function relationships of cation binding in the Na+/K(+)-ATPase.

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Aldose reductase inhibitors: the end of an era or the need for different trial designs?

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The role of protein kinase C in transmembrane signalling

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Glucose-induced oxidative stress in vascular contractile cells: comparison of aortic smooth muscle cells and retinal pericytes

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Age-dependent increase in ortho-tyrosine and methionine sulfoxide in human skin collagen is not accelerated in diabetes. Evidence against a generalized increase in oxidative stress in diabetes

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Antioxidant nutrient intake and diabetic retinopathy: the San Luis Valley Diabetes Study

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Advanced glycosylation end products in patients with diabetic nephropathy

21 January 2018

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Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications

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Diabetic retinopathy. A synthesis of perspectives

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Glycation products and the pathogenesis of diabetic complications

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Characterization of the advanced glycation end-product receptor complex in human vascular endothelial cells

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High glucose induces DNA damage in cultured human endothelial cells

21 January 2018

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Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes

21 January 2018

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Constitutive nitric oxide synthase expression in retinal vascular endothelial cells is suppressed by high glucose and advanced glycation end products.

21 January 2018

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Tobacco smoke is a source of toxic reactive glycation products

21 January 2018

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The 14-year incidence of visual loss in a diabetic population

21 January 2018

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

21 January 2018

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Role of leukocytes in diabetic microcirculatory disturbances

21 January 2018

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Neutrophils plug capillaries in acute experimental retinal ischemia

21 January 2018

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Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy

21 January 2018

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

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Apoptosis in ocular disease: a molecular overview

21 January 2018

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A model for p53-induced apoptosis

21 January 2018

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Retinal vascular autoregulation in diabetes mellitus.

21 January 2018

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Oxygen reactivity in diabetes mellitus: effect of hypertension and hyperglycaemia

21 January 2018

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Retinal oxygen consumption during hyperglycemia in patients with diabetes without retinopathy

21 January 2018

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Laser Doppler velocimetry study of retinal circulation in diabetes mellitus

21 January 2018

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Retinal blood flow in diabetic retinopathy

21 January 2018

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The effect of endothelin 1 on the retinal microvascular pericyte

21 January 2018

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Induction of resistance to endothelin-1's biochemical actions by elevated glucose levels in retinal pericytes

21 January 2018

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Non-retinovascular leakage in diabetic maculopathy

21 January 2018

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Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group

21 January 2018

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Electron microscopic immunocytochemical demonstration of blood-retinal barrier breakdown in human diabetics and its association with aldose reductase in retinal vascular endothelium and retinal pigment epithelium.

21 January 2018

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Ultrastructure of retinal vessels in diabetic patients

21 January 2018

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The effect of diabetes on blood flow properties

21 January 2018

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Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells

21 January 2018

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Growth factors in angiogenesis: current interest and therapeutic potential

21 January 2018

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Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primate

21 January 2018

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Systemic hyperoxia decreases vascular endothelial growth factor gene expression in ischemic primate retina

21 January 2018

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Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

21 January 2018

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Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

21 January 2018

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Radiation retinopathy--clinical, histopathological, ultrastructural and experimental correlations

21 January 2018

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Diabetic retinopathy: quantitative variation in capillary basement membrane thickening in arterial or venous environments.

21 January 2018

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Increased expression of basement membrane collagen in human diabetic retinopathy

21 January 2018

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https://api.crossref.org/works/10.1038%2FEYE.1999.130

Increased expression of basement membrane components in human endothelial cells cultured in high glucose

21 January 2018

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https://api.crossref.org/works/10.1038%2FEYE.1999.130

Aminoguanidine treatment inhibits the development of experimental diabetic retinopathy

21 January 2018

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Histological and ultrastructural investigation of retinal microaneurysm development in diabetic patients

21 January 2018

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Retinal microcirculation in patients with diabetes mellitus: dynamic and morphological analysis of perifoveal capillary network

21 January 2018

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Biochemical abnormalities in vitreous of humans with proliferative diabetic retinopathy

21 January 2018

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Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases

21 January 2018

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Vascular endothelial growth factor is a secreted angiogenic mitogen

21 January 2018

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Vascular endothelial growth factor and the eye: biochemical mechanisms of action and implications for novel therapies

21 January 2018

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Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth

21 January 2018

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Vitreous levels of the insulin-like growth factors I and II, and the insulin-like growth factor binding proteins 2 and 3, increase in neovascular eye disease. Studies in nondiabetic and diabetic subjects

21 January 2018

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Correlation of fibrosis and transforming growth factor-beta type 2 levels in the eye

21 January 2018

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Intravitreal growth factors in proliferative diabetic retinopathy: correlation with neovascular activity and glycaemic management

21 January 2018

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Prevalence and associations of epiretinal membranes. The Blue Mountains Eye Study, Australia.

21 January 2018

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Insulin prophylaxis in individuals at high risk of type I diabetes

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Seminars in medicine of the Beth Israel Hospital, Boston: Pancreatic and islet transplantation for diabetes--cures or curiosities?

21 January 2018

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Recent achievements in experimental and clinical islet transplantation

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

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Science, medicine, and the future. Non-insulin dependent diabetes mellitus: the gathering storm

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Retinopathy in galactosemic dogs continues to progress after cessation of galactosemia.

21 January 2018

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Vitamin E and cardiovascular protection in diabetes

21 January 2018

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Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking

21 January 2018

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An agent cleaving glucose-derived protein crosslinks in vitro and in vivo

21 January 2018

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Endothelium-dependent inhibition of Na(+)-K+ ATPase activity in rabbit aorta by hyperglycemia. Possible role of endothelium-derived nitric oxide

21 January 2018

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Prevention of experimental proliferative vitreoretinopathy with a biodegradable intravitreal implant for the sustained release of fluorouracil

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Induction of neoangiogenesis in ischemic myocardium by human growth factors: first clinical results of a new treatment of coronary heart disease

21 January 2018

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Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate

21 January 2018

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Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

21 January 2018

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Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy

21 January 2018

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Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy

21 January 2018

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Astrocytes induce blood–brain barrier properties in endothelial cells

21 January 2018

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Toxic action of advanced glycation end products on cultured retinal capillary pericytes and endothelial cells: relevance to diabetic retinopathy

21 January 2018

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Ocular vascular endothelial growth factor levels in diabetic rats are elevated before observable retinal proliferative changes

21 January 2018

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The Wisconsin epidemiologic study of diabetic retinopathy. II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years

21 January 2018

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7 January 2021

The Wisconsin epidemiologic study of diabetic retinopathy. III. Prevalence and risk of diabetic retinopathy when age at diagnosis is 30 or more years

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7 January 2021

Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group

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7 January 2021

Glycogen accumulation in retinal neurons and glial cells of streptozotocin-diabetic rats. Quantitative electron microscopy

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7 January 2021

Hyperglycemic pseudohypoxia and diabetic complications.

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7 January 2021

Aldose reductase inhibition fails to prevent retinopathy in diabetic and galactosemic dogs

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7 January 2021

The effect of high glucose on polyol pathway activity and myoinositol metabolism in cultured human endothelial cells

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7 January 2021

Nerve conduction and aldose reductase inhibition during 5 years of diabetes or galactosaemia in dogs

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7 January 2021

Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor

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7 January 2021

Role of oxidative stress in development of complications in diabetes

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7 January 2021

Impaired activation of glucose oxidation and NADPH supply in human endothelial cells exposed to H2O2 in high-glucose medium

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7 January 2021

The glutathione levels are reduced in Goto-Kakizaki rat retina, but are not influenced by aminoguanidine treatment

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7 January 2021

Toxicity of mildly modified low-density lipoproteins to cultured retinal capillary endothelial cells and pericytes

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7 January 2021

Abnormalities of retinal metabolism in diabetes or experimental galactosemia. III. Effects of antioxidants

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7 January 2021

Increased levels of advanced glycation endproducts in the lenses and blood vessels of cigarette smokers.

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7 January 2021

Cigarette smoking and ten-year progression of diabetic retinopathy

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7 January 2021

Decreased deformability of polymorphonuclear leukocytes in diabetic cats

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7 January 2021

Stereological estimation of Weibel-Palade bodies in the retinal vasculature of normal and diabetic dogs

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7 January 2021

The central executioners of apoptosis: caspases or mitochondria?

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7 January 2021

Altered Retinal Vascular Response to 100% Oxygen Breathing in Diabetes Mellitus

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7 January 2021

Reversal of abnormal retinal hemodynamics in diabetic rats by acarbose, an alpha-glucosidase inhibitor

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7 January 2021

Effect of an insulin-induced decrease in blood glucose on the human diabetic retinal circulation

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https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Diabetic glycemic control and retinal blood flow

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Augmented retinal endothelin-1, endothelin-3, endothelinA and endothelinB gene expression in chronic diabetes

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Endothelin-1 and endothelin-3-like immunoreactivity in the eyes of diabetic and non-diabetic BB/W rats

1 reference

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7 January 2021

Characterization of the early stages of diabetic retinopathy by vitreous fluorophotometry

1 reference

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7 January 2021

Certain Histological and Chemical Responses of the Vascular Interface to Acutely Induced Mechanical Stress in the Aorta of the Dog

1 reference

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7 January 2021

Insulin-like growth factor-1 retinal microangiopathy in the pig eye

1 reference

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7 January 2021

Expression of vascular endothelial growth factor (VEGF) and its receptors is regulated in eyes with intra-ocular tumours

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Vascular endothelial growth factor in ocular neovascularization and proliferative diabetic retinopathy.

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Glucose-induced protein kinase C activation regulates vascular permeability factor mRNA expression and peptide production by human vascular smooth muscle cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Vascular endothelial growth factor upregulation in human central retinal vein occlusion

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Vascular endothelial growth factor plays a role in hyperpermeability of diabetic retinal vessels

1 reference

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7 January 2021

The combined effects of diabetes and ionising radiation on the rat retina: an ultrastructural study

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Increased endocytosis in retinal vascular endothelial cells grown in high glucose medium is modulated by inhibitors of nonenzymatic glycosylation

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Retinopathy in animal models of diabetes

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https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Retinal vascular patterns. IV. Diabetic retinopathy

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7 January 2021

Retinal vascular patterns. VI. Mural cells of the retinal capillaries

1 reference

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7 January 2021

Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Increased level of vascular endothelial growth factor in aqueous humor of patients with neovascular glaucoma

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Extracellular modulating factors and the control of intraocular neovascularization. An overview

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7 January 2021

Basic Fibroblast Growth Factor Levels in the Vitreous of Patients With Proliferative Diabetic Retinopathy

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https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Prevention or delay of Type 1 (insulin-dependent) diabetes mellitus in children using nicotinamide

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7 January 2021

Progression of diabetic retinopathy after pancreas transplantation for insulin-dependent diabetes mellitus

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https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Progression of diabetic retinopathy after pancreas transplantation. The University of Michigan Pancreas Transplant Evaluation Committee

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https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Pancreas transplantation in humans with diabetes mellitus

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https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Progression of incipient diabetic retinopathy during good glycemic control.

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Normalization of diacylglycerol-protein kinase C activation by vitamin E in aorta of diabetic rats and cultured rat smooth muscle cells exposed to elevated glucose levels

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

An aldose reductase inhibitor and aminoguanidine prevent vascular endothelial growth factor expression in rats with long-term galactosemia

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Effect of sorbinil on blood-retinal barrier in early diabetic retinopathy

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Protective effect of captopril on the blood-retina barrier in normotensive insulin-dependent diabetic patients with nephropathy and background retinopathy

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Alterations in retinal Na+, K(+)-ATPase in diabetes: streptozotocin-induced and Zucker diabetic fatty rats

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

An intravitreal sustained-release triamcinolone and 5-fluorouracil codrug in the treatment of experimental proliferative vitreoretinopathy

1 reference

https://api.crossref.org/works/10.1038%2FEYE.1999.130

7 January 2021

Identifiers

DOI

10.1038/EYE.1999.130

1 reference

13 February 2018

1 reference

13 February 2018