(Q48614262)

13 February 2018

title

The Na+/H+ exchanger-1 inhibitor cariporide prevents glutamate-induced necrotic neuronal death by inhibiting mitochondrial Ca2+ overload (English)

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author name string

Bo Kyung Lee

series ordinal

1

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Yi-Sook Jung

series ordinal

2

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publication date

1 April 2012

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Journal of Neuroscience Research

published in

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volume

90

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issue

4

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page(s)

860-869

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13 February 2018

Mechanistically distinct steps in the mitochondrial death pathway triggered by oxidative stress in cardiac myocytes

cites work

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A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.

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Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity

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Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage

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Excitotoxic cell death

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Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties

21 January 2018

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Calcium sequestering ability of mitochondria modulates influx of calcium through glutamate receptor channel.

21 January 2018

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KR-32570, a novel Na+/H+ exchanger-1 inhibitor, attenuates hypoxia-induced cell death through inhibition of intracellular Ca2+ overload and mitochondrial death pathway in H9c2 cells

21 January 2018

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The mitochondrial death/life regulator in apoptosis and necrosis

21 January 2018

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Decreased neuronal death in Na+/H+ exchanger isoform 1-null mice after in vitro and in vivo ischemia.

21 January 2018

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Na+/H+ exchanger inhibitor, SM-20220, is protective against excitotoxicity in cultured cortical neurons

21 January 2018

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Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore

21 January 2018

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Mitochondrial dysfunction and glutamate excitotoxicity studied in primary neuronal cultures

21 January 2018

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alpha-Amino-3-hydroxy-5-methyl-4-isoxazole propionate attenuates glutamate-induced caspase-3 cleavage via regulation of glycogen synthase kinase 3beta

21 January 2018

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Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia

21 January 2018

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Mitochondrial Ca2+-activated K+ channels in cardiac myocytes: a mechanism of the cardioprotective effect and modulation by protein kinase A.

21 January 2018

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The regulation of reactive oxygen species production during programmed cell death

21 January 2018

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Cariporide (HOE642), a Selective Na + -H + Exchange Inhibitor, Inhibits the Mitochondrial Death Pathway

21 January 2018

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Selective loading of Rhod 2 into mitochondria shows mitochondrial Ca2+ transients during the contractile cycle in adult rabbit cardiac myocytes.

21 January 2018

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Ca2+-induced permeabilization promotes free radical release from rat brain mitochondria with partially inhibited complex I.

21 January 2018

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Gene inactivation of Na+/H+ exchanger isoform 1 attenuates apoptosis and mitochondrial damage following transient focal cerebral ischemia

21 January 2018

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Sustained calpain activation associated with lysosomal rupture executes necrosis of the postischemic CA1 neurons in primates

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JNR.22818

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13 February 2018