(Q48627169)

English

The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed.

scientific article published in November 1997

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scholarly article

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed. (English)

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

long-term potentiation

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based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

author name string

McGahon B

1

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

Clements MP

2

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

language of work or name

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publication date

1 November 1997

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

81

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

1

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

9-16

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

Release of neurotransmitter amino acids from rat brain synaptosomes and its regulation in aging.

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Effects of aging on the dynamics of information processing and synaptic weight changes in the mammalian hippocampus.

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Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors.

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Protein kinase C activity, translocation, and conventional isoforms in aging rat brain

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A synaptic model of memory: long-term potentiation in the hippocampus

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Decreased density, but not number, of N-methyl-D-aspartate, glycine and phencyclidine binding sites in hippocampus of senescent rats.

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Antagonists of the metabotropic glutamate receptor do not prevent induction of long-term potentiation in the dentate gyrus of rats.

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Arachidonic acid and diacylglycerol ACT synergistically through protein kinase C to persistently enhance synaptic transmission in the hippocampus.

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Biochemical changes of rat brain membranes with aging

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LTP in the dentate gyrus is associated with a persistent NMDA receptor-dependent enhancement of synaptosomal glutamate release

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Increase in arachidonic acid concentration in a postsynaptic membrane fraction following the induction of long-term potentiation in the dentate gyrus

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Co-administration of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid and arachidonic acid potentiates synaptic transmission in rat hippocampal slices.

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Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

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Acetyl-L-carnitine: behavioral, electrophysiological, and neurochemical effects.

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Electrophysiological markers of aging and memory loss in rats.

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Selective reduction of hippocampal dentate frequency potentiation in aged rats with impaired place learning.

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Effect of age on brain cortical protein kinase C and its mediation of 5-hydroxytryptamine release

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The aging brain. A normal phenomenon with not-so-normal arachidonic acid metabolism

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Protection of neocortical tissue prisms from freeze-thaw injury by dimethyl sulphoxide

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Positive feedback of glutamate exocytosis by metabotropic presynaptic receptor stimulation

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Impaired Monosynaptic Potentiation in in Vitro Hippocampal Slices From Aged, Memory-deficient Rats

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Impaired synaptic potentiation processes in the hippocampus of aged, memory-deficient rats

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Arachidonic acid increases inositol phospholipid metabolism and glutamate release in synaptosomes prepared from hippocampal tissue

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Nordihydroguaiaretic acid blocks the synaptic component of long-term potentiation and the associated increases in release of glutamate and arachidonate: An in vivo study in the dentate gyrus of the rat

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Membrane arachidonic acid concentration correlates with age and induction of long-term potentiation in the dentate gyrus in the rat.

1 reference

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Effect of bromophenacyl bromide, a phospholipase A2 inhibitor, on the induction and maintenance of LTP in hippocampal slices

1 reference

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A study of the synergism between metabotropic glutamate receptor activation and arachidonic acid in the rat hippocampus

1 reference

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The synergism between metabotropic glutamate receptor activation and arachidonic acid on glutamate release is occluded by induction of long-term potentiation in the dentate gyrus

1 reference

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The synergism between ACPD and arachidonic acid on glutamate release in hippocampus is age-dependent.

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Assay of free and total fatty acids (as 2-nitrophenylhydrazides) by high performance liquid chromatography

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Ageing is associated with changes in glutamate release, protein tyrosine kinase and Ca2+/calmodulin-dependent protein kinase II in rat hippocampus.

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Diminished calcium currents in aged hippocampal dentate gyrus granule neurones

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Activation of metabotropic glutamate receptors is necessary for long-term potentiation in the dentate gyrus and for spatial learning.

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Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus

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An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses

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Identifiers

10.1016/S0306-4522(97)00116-4

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9300396

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