(Q48630088)

English

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

scientific article published in September 1997

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278541%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278541%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

M C Irizarry

1

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5 November 2019

F Soriano

2

1 reference

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5 November 2019

M McNamara

3

1 reference

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5 November 2019

K J Page

4

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5 November 2019

D Schenk

5

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5 November 2019

D Games

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278541%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

B T Hyman

7

1 reference

Europe PubMed Central

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5 November 2019

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publication date

1 September 1997

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Europe PubMed Central

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5 November 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278541%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

17

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Europe PubMed Central

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5 November 2019

18

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278541%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

7053-7059

1 reference

Europe PubMed Central

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5 November 2019

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unbiased stereological estimation of the number of neurons in the human hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible role of apoptosis in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological stageing of Alzheimer-related changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regional and cellular distribution of beta-amyloid precursor protein messenger RNAs containing and lacking the Kunitz protease inhibitor domain in the brain of human, rat and mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Re-evaluation of the structural organization of neuritic plaques in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and pathological correlates of apolipoprotein E ?4 in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ hybridization analysis of presenilin 1 mRNA in Alzheimer disease and in lesioned rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of neuronal mRNAs in Alzheimer type degeneration of the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal activity and early neurofibrillary tangles in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid fibril toxicity in Alzheimer's disease and diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional alterations in Alzheimer's disease: selective loss of mitochondrial-encoded cytochrome oxidase mRNA in the hippocampal formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant GAP-43 gene expression in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plaques, tangles and dementia. A quantitative study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New stereological methods for counting neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of Alzheimer pathology after beta-amyloid protein injections in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for beta-APP751.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perforant pathway changes and the memory impairment of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reorganization of cingulate cortex in Alzheimer's disease: neuron loss, neuritic plaques, and muscarinic receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurons bearing neurofibrillary tangles are responsible for selected synaptic deficits in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The acute neurotoxicity and effects upon cholinergic axons of intracerebrally injected beta-amyloid in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of neuronal death in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative roles of plaques and tangles in the dementia of Alzheimer's disease: correlations using three sets of neuropathological criteria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic and neuroprotective effects of hAPP in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic amyloid beta-protein fails to produce specific neurotoxicity in monkey cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure of beta-amyloid protein fragment 25-35 to cause hippocampal damage in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9278541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.17-18-07053.1997

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278541%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278541%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278541%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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