(Q48655836)

English

Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease.

scientific article published in July 1997

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease. (English)

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

Alzheimer's disease

0 references

0 references

1 reference

based on heuristic

inferred from title

author name string

Grynspan F

1

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

Griffin WR

2

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

Cataldo A

3

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

Katayama S

4

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

Nixon RA

5

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

language of work or name

0 references

publication date

1 July 1997

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

number of pages

14

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

763

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

2

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

145-158

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

Alzheimer's disease. Paired helical filaments and the cytoskeleton.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calpain inhibitors improve the recovery of synaptic transmission from hypoxia in hippocampal slices

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Distribution of calcium activated neutral proteinase (mM CANP) in myelin and cytosolic fractions in bovine brain white matter.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

The distribution of tau in the mammalian central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

In vitro digestion of spectrin, protein 4.1 and ankyrin by erythrocyte calcium dependent neutral protease (calpain I)

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Immunohistochemical staging of neurofibrillary degeneration in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Absence of abnormal hyperphosphorylation of tau in intracellular tangles in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Structural modifications associated with the change in Ca2+ sensitivity on activation of m-calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Characterization and comparison of neurofilament proteins from rat and mouse CNS

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Polyclonal antisera specific for the proenzyme form of each calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calcium-activated neutral protease (calpain) system: structure, function, and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Comparison of the autolyzed and unautolyzed forms of mu- and m-calpain from bovine skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calpain-mediated proteolysis of microtubule associated proteins MAP1B and MAP2 in developing brain

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Immunohistochemical distribution of calcium-activated neutral proteinases and endogenous CANP inhibitor in the rabbit hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Solubilization and fractionation of paired helical filaments.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Phosphorylation modulates calpain-mediated proteolysis and calmodulin binding of the 200-kDa and 160-kDa neurofilament proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Distribution of calpains I and II in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Proteolytic processing of human brain alpha spectrin (fodrin): identification of a hypersensitive site.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Hydrolytic and autolytic behavior of two forms of calcium-activated neutral protease (CANP).

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Are Alzheimer neurofibrillary tangles insoluble polymers?

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Defective brain microtubule assembly in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Alzheimer paired helical filaments: bulk isolation, solubility, and protein composition

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

A Calcium-Activated Protease which Preferentially Degrades the 160-kDa Component of the Neurofilament Triplet

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Demonstration of neurofibrillary tangles in parvalbumin-immunoreactive interneurones in the cerebral cortex of Alzheimer-type dementia brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Localization of calpain immunoreactivity in senile plaques and in neurones undergoing neurofibrillary degeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calpain-mediated proteolysis of microtubule-associated protein 2 (MAP-2) is inhibited by phosphorylation by cAMP-dependent protein kinase, but not by Ca2+/calmodulin-dependent protein kinase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Proteolysis of tau by calpain.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Increased proteolytic activity in lymphocytes from patients with early onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calcium, membranes, aging, and Alzheimer's disease. Introduction and overview.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calcium-dependent neural proteases, widespread occurrence of a species of protease active at lower concentrations of calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Mass and physical dimensions of two distinct populations of paired helical filaments.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Immunological and conformation characterization of a phosphorylated immunodominant epitope on the paired helical filaments found in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Isolation of a phosphorylated soluble tau fraction from Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Chemically synthesized peptides predicted from the nucleotide sequence of the hepatitis B virus genome elicit antibodies reactive with the native envelope protein of Dane particles

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Regional differences in gene expression for calcium activated neutral proteases (calpains) and their endogenous inhibitor calpastatin in mouse brain and spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Phosphorylation of tau in situ: inhibition of calcium-dependent proteolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Phosphorylation, calpain proteolysis and tubulin binding of recombinant human tau isoforms.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Modulation of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/quisqualate receptors by phospholipase A2: a necessary step in long-term potentiation?

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Canine cardiac calcium-dependent proteases: Resolution of two forms with different requirements for calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Ubiquitin is a component of paired helical filaments in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Specific increase in calcium-activated neutral protease with low calcium sensitivity (m-calpain) in proerythroblastic K562 cell line cells induced to differentiation by phorbol 12-myristate 13-acetate

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

A modified form of microtubule-associated tau protein is the main component of paired helical filaments.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calcium-activated neutral proteinases as regulators of cellular function. Implications for Alzheimer's disease pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Limited proteolytic modification of a neurofilament protein involves a proteinase activated by endogenous levels of calcium.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Multiple calcium-activated neutral proteinases (CANP) in mouse retinal ganglion cell neurons: specificities for endogenous neuronal substrates and comparison to purified brain CANP.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.51

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Dephosphorylation of neurofilament proteins enhances their susceptibility to degradation by calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Increased spectrin proteolysis in fibroblasts from aged and Alzheimer donors

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Identification of the proteolytically activated form of protein kinase C in stimulated human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Cytoskeletal derangements of cortical neuronal processes three hours after traumatic brain injury in rats: an immunofluorescence study

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Autolytic Transition of μCalpain upon Activation as Resolved by Antibodies Distinguishing between the Pre- and Post-Autolysis Forms1

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Distinct kinetics of subunit autolysis in mammalian m-calpain activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Identification and characterization of membrane-bound calpains in clathrin-coated vesicles from bovine brain

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Ischemia triggers NMDA receptor-linked cytoskeletal proteolysis in hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Enhancement of neurite outgrowth following calpain inhibition is mediated by protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calcium influx into human neuroblastoma cells induces ALZ-50 immunoreactivity: involvement of calpain-mediated hydrolysis of protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Presence of calpain II immunoreactivity in senile plaques in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Evidence for the association of protein 4.1 immunoreactive forms with neurofibrillary tangles in Alzheimer's disease brains

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Brain fodrin: substrate for calpain I, an endogenous calcium-activated protease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calcium activated neutral protease--structure-function relationship and functional implications

2 references

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunoassay and activity of calcium-activated neutral proteinase (mCANP): distribution in soluble and membrane-associated fractions in human and mouse brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Localization of the mitogen activated protein kinase ERK2 in Alzheimer's disease neurofibrillary tangles and senile plaque neurites.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calcium-activated neutral proteinase of human brain: subunit structure and enzymatic properties of multiple molecular forms.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Structural characterization of the core of the paired helical filament of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calpain-induced proteolysis of normal human tau and tau associated with paired helical filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

Calcium-activated neutral proteinase (calpain) system in aging and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid proteolysis of brain MAP-1 related cytoskeleton-associated 350kd protein by purified calpain.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900384-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0006-8993(97)00384-3

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/9296555

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q48655836&oldid=1950403684"