(Q48659334)

14 February 2018

title

NMDA receptors participate in the progression of diabetic kidney disease by decreasing Cdc42-GTP activation in podocytes (English)

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14 February 2018

author name string

Jia Shen

1

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14 February 2018

Rending Wang

2

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14 February 2018

Zhechi He

3

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14 February 2018

Hongfeng Huang

4

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14 February 2018

Xuelin He

5

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14 February 2018

Jingyi Zhou

6

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14 February 2018

Yinggang Yan

7

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14 February 2018

Shuijuan Shen

8

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14 February 2018

Xue Shao

9

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14 February 2018

Xiujin Shen

10

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14 February 2018

Chunhua Weng

11

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14 February 2018

Weiqiang Lin

12

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14 February 2018

Jianghua Chen

13

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14 February 2018

publication date

24 June 2016

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14 February 2018

published in

Journal of Pathology

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14 February 2018

volume

240

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14 February 2018

issue

2

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14 February 2018

page(s)

149-160

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14 February 2018

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis

cites work

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NMDA receptor blocker ameliorates ischemia-reperfusion-induced renal dysfunction in rat kidneys

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Renal NMDA receptors independently stimulate proximal reabsorption and glomerular filtration

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Functional NMDA receptors with atypical properties are expressed in podocytes

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Sustained activation of N-methyl-D-aspartate receptors in podoctyes leads to oxidative stress, mobilization of transient receptor potential canonical 6 channels, nuclear factor of activated T cells activation, and apoptotic cell death

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The genetics of hypertension modifies the renal cell replication response induced by experimental diabetes

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The β isoform of GSK3 mediates podocyte autonomous injury in proteinuric glomerulopathy

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Mesangial cell NADPH oxidase upregulation in high glucose is protein kinase C dependent and required for collagen IV expression

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Altered NMDA receptor expression in renal toxicity: Protection with a receptor antagonist

21 January 2018

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The role of ionotropic receptors of glutaminic acid in cardiovascular system. A. The influence of ionotropic receptor NMDA agonist - 1R,3R-ACPD and antagonist - DL-AP7 on the systemic pressure in rats

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In vivo gene transfer to kidney by lentiviral vector

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KIBRA modulates directional migration of podocytes

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High glucose increases glomerular filtration barrier permeability by activating protein kinase G type Iα subunits in a Nox4-dependent manner.

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Role of protein kinase C in podocytes and development of glomerular damage in diabetic nephropathy

21 January 2018

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An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits

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Coordinated PKA and PKC phosphorylation suppresses RXR-mediated ER retention and regulates the surface delivery of NMDA receptors

21 January 2018

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Serines 890 and 896 of the NMDA receptor subunit NR1 are differentially phosphorylated by protein kinase C isoforms.

21 January 2018

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Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton

21 January 2018

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Rho-family small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro

21 January 2018

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Role of Rho-GTPases and their regulatory proteins in glomerular podocyte function

21 January 2018

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Cdc42 coordinates proliferation, polarity, migration, and differentiation of small intestinal epithelial cells in mice

21 January 2018

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Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts

21 January 2018

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Involvement of Rho-family GTPases in axon branching

21 January 2018

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Characterization of a Cdc42 protein inhibitor and its use as a molecular probe

21 January 2018

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Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes

21 January 2018

1 reference

Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis

21 January 2018

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Cdc42 is required for cytoskeletal support of endothelial cell adhesion during blood vessel formation in mice

21 January 2018

1 reference

NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells.

21 January 2018

1 reference

Pharmacological Inhibition of N-Methyl D-Aspartate Receptor Promotes Secretion of Vascular Endothelial Growth Factor in Müller Cells: Effects of Hyperglycemia and Hypoxia

21 January 2018

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Activation of NMDA receptors increases proliferation and differentiation of hippocampal neural progenitor cells

21 January 2018

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VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation

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21 January 2018

Identifiers

DOI

10.1002/PATH.4764

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14 February 2018

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14 February 2018