(Q48790396)

15 February 2018

title

A beta deposition inhibitor screen using synthetic amyloid. (English)

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15 February 2018

author name string

Esler WP

1

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15 February 2018

Stimson ER

2

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15 February 2018

Ghilardi JR

3

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15 February 2018

Felix AM

4

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15 February 2018

Lu YA

5

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15 February 2018

Vinters HV

6

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15 February 2018

Mantyh PW

7

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15 February 2018

Maggio JE

8

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15 February 2018

publication date

1 March 1997

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15 February 2018

published in

Nature Biotechnology

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15 February 2018

volume

15

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15 February 2018

page(s)

258-263

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15 February 2018

issue

3

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15 February 2018

https://scigraph.springernature.com/pub.10.1038/nbt0397-258

exact match

0 references

cites work

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The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

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Genetic dissection of Alzheimer disease, a heterogeneous disorder

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

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7 January 2021

Amyloid beta-peptide is produced by cultured cells during normal metabolism

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7 January 2021

Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro

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Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

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beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

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7 January 2021

Inhibition of amyloid beta protein aggregation and neurotoxicity by rifampicin. Its possible function as a hydroxyl radical scavenger.

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Sulfonated dyes attenuate the toxic effects of beta-amyloid in a structure-specific fashion

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7 January 2021

Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation

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Brain amyloid--a physicochemical perspective

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7 January 2021

On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants

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7 January 2021

In vitro growth of Alzheimer's disease beta-amyloid plaques displays first-order kinetics.

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7 January 2021

Reversible in vitro growth of Alzheimer disease beta-amyloid plaques by deposition of labeled amyloid peptide

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7 January 2021

1H NMR of A beta amyloid peptide congeners in water solution. Conformational changes correlate with plaque competence

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7 January 2021

Point substitution in the central hydrophobic cluster of a human beta-amyloid congener disrupts peptide folding and abolishes plaque competence

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Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

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Alternative conformations of amyloidogenic proteins govern their behavior

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Quantitative analysis of senile plaques in Alzheimer disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome).

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7 January 2021

Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein

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7 January 2021

Zinc-induced aggregation of human and rat beta-amyloid peptides in vitro.

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7 January 2021

Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide.

1 reference

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7 January 2021

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

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7 January 2021

Identifiers

DOI

10.1038/NBT0397-258

1 reference

15 February 2018

PubMed ID

9062926

1 reference

15 February 2018