(Q48792346)

15 February 2018

title

Gemfibrozil and its glucuronide inhibit the hepatic uptake of pravastatin mediated by OATP1B1. (English)

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15 February 2018

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R Nakagomi-Hagihara

1

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15 February 2018

D Nakai

2

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15 February 2018

T Tokui

3

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15 February 2018

T Abe

4

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15 February 2018

T Ikeda

5

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15 February 2018

language of work or name

English

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publication date

1 May 2007

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15 February 2018

published in

Xenobiotica

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15 February 2018

volume

37

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15 February 2018

issue

5

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15 February 2018

page(s)

474-486

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15 February 2018

Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1

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1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Cerivastatin and gemfibrozil-associated rhabdomyolysis

21 January 2018

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The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability

21 January 2018

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Rhabdomyolysis with HMG-CoA reductase inhibitors and gemfibrozil combination therapy

21 January 2018

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Maintenance of Xenopus laevis and oocyte injection

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Clinical pharmacokinetics of pravastatin: mechanisms of pharmacokinetic events

21 January 2018

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https://api.crossref.org/works/10.1080%2F00498250701278442

Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Vectorial transport of the peptide CCK-8 by double-transfected MDCKII cells stably expressing the organic anion transporter OATP1B3 (OATP8) and the export pump ABCC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/

21 January 2018

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Clinical pharmacokinetics of fibric acid derivatives (fibrates).

21 January 2018

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https://api.crossref.org/works/10.1080%2F00498250701278442

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: implications for drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Mechanistic studies on metabolic interactions between gemfibrozil and statins

21 January 2018

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https://api.crossref.org/works/10.1080%2F00498250701278442

Severe rhabdomyolysis and cerivastatin-gemfibrozil combination therapy

21 January 2018

1 reference

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Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug inter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Pravastatin, an HMG-CoA reductase inhibitor, is transported by rat organic anion transporting polypeptide, oatp2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250701278442

10.1080/00498250701278442

21 January 2018

Identifiers

DOI

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15 February 2018

1 reference

15 February 2018