(Q48829616)

English

Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-beta peptide (1-40).

scientific article published in December 1996

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8987819%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-beta peptide (1-40) (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8987819%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

author name string

J R Backstrom

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

G P Lim

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

M J Cullen

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

Z A Tökés

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

language of work or name

0 references

publication date

1 December 1996

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8987819%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

16

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

24

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

7910-7919

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

Proteolysis of A beta peptide from Alzheimer disease brain by gelatinase A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnosis of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor promoter-stimulated Mr 92,000 gelatinase secreted by normal and malignant human cells: isolation and characterization of the enzyme from HT1080 tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a metalloprotease from Alzheimer's disease brain able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Neutral Proteinases from Alzheimer-Affected and Control Brain Specimens: Identification of Calcium-Dependent Metalloproteinases from the Hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of amyloid beta peptide during constitutive processing of its precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of human neutrophil gelatinase by endogenous serine proteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of matrix metalloproteinase 9 from U937 monocytic leukaemia and HT1080 fibrosarcoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 84-kDa form of human matrix metalloproteinase-9 degrades substance P and gelatin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases in the neocortex and spinal cord of amyotrophic lateral sclerosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A latent Mr 94,000 gelatin-degrading metalloprotease induced during differentiation of HL-60 promyelocytic leukemia cells: a member of the collagenase family of enzymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative measurement of relative gene expression in human tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory mechanisms in Alzheimer's disease: implications for therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of a novel metalloprotease from human brain with the ability to cleave substrates derived from the N-terminus of beta-amyloid protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative sequence specificities of human 72- and 92-kDa gelatinases (type IV collagenases) and PUMP (matrilysin)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of human glomerular basement membrane by stimulated neutrophils. Activation of a metalloproteinase(s) by reactive oxygen metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of age and Alzheimer's disease on pyramidal neuron density in the individual fields of the hippocampal formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The latent collagenase and gelatinase of human polymorphonuclear neutrophil leucocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteins of the kidney microvillar membrane. The amphipathic forms of endopeptidase purified from pig kidneys

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix degrading metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and expression of neutrophil gelatinase cDNA. Identity with type IV collagenase from HT1080 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The processing of Alzheimer A4/beta-amyloid protein precursor: identification of a human brain metallopeptidase which cleaves -Lys-Leu- in a model peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/8987819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.16-24-07910.1996

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579235&resulttype=core&format=json

15 May 2020

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