(Q48834619)

16 February 2018

title

Negative charges in the DIII-DIV linker of human skeletal muscle Na+ channels regulate deactivation gating. (English)

1 reference

16 February 2018

author name string

James R Groome

series ordinal

1

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16 February 2018

Esther Fujimoto

series ordinal

2

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16 February 2018

Peter C Ruben

series ordinal

3

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16 February 2018

language of work or name

English

0 references

publication date

14 February 2003

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16 February 2018

published in

Journal of Physiology

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16 February 2018

volume

548

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16 February 2018

issue

Pt 1

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16 February 2018

page(s)

85-96

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16 February 2018

A quantitative description of membrane current and its application to conduction and excitation in nerve

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Slow inactivation in voltage-gated sodium channels: molecular substrates and contributions to channelopathies

26 August 2018

1 reference

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Outer and central charged residues in DIVS4 of skeletal muscle sodium channels have differing roles in deactivation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Contributions of charged residues in a cytoplasmic linking region to Na channel gating

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Immobilizing the moving parts of voltage-gated ion channels

26 August 2018

1 reference

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The delay in recovery from fast inactivation in skeletal muscle sodium channels is deactivation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Role of domain 4 in sodium channel slow inactivation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Movement of voltage sensor S4 in domain 4 is tightly coupled to sodium channel fast inactivation and gating charge immobilization

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Differential effects of homologous S4 mutations in human skeletal muscle sodium channels on deactivation gating from open and inactivated states.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Voltage sensors in domains III and IV, but not I and II, are immobilized by Na+ channel fast inactivation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Solution structure of the sodium channel inactivation gate

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Independent versus coupled inactivation in sodium channels. Role of the domain 2 S4 segment

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Sodium channel inactivation is altered by substitution of voltage sensor positive charges

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Sodium channel activation gating is affected by substitutions of voltage sensor positive charges in all four domains

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Molecular analysis of the putative inactivation particle in the inactivation gate of brain type IIA Na+ channels

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

A unique role for the S4 segment of domain 4 in the inactivation of sodium channels

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Movement of the Na+ channel inactivation gate during inactivation.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Inactivation defects caused by myotonia-associated mutations in the sodium channel III-IV linker

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Molecular basis of charge movement in voltage-gated sodium channels

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Genomic organization of the human skeletal muscle sodium channel gene

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Na+ channels must deactivate to recover from inactivation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Primary structure and functional expression of a mammalian skeletal muscle sodium channel

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Sodium channel gating in clonal pituitary cells. The inactivation step is not voltage dependent

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Changes in sodium channel gating produced by point mutations in a cytoplasmic linker

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Amino acid residues required for fast Na(+)-channel inactivation: charge neutralizations and deletions in the III-IV linker

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Inactivation of the sodium channel. II. Gating current experiments

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342797

Identification of an intracellular peptide segment involved in sodium channel inactivation

26 August 2018

1 reference

12 December 2020

Structural parts involved in activation and inactivation of the sodium channel

1 reference

12 December 2020

Evidence for voltage-dependent S4 movement in sodium channels

1 reference

12 December 2020

A defect in skeletal muscle sodium channel deactivation exacerbates hyperexcitability in human paramyotonia congenita

1 reference

12 December 2020

10.1113/JPHYSIOL.2002.033084

Identifiers

DOI

1 reference

16 February 2018

PMC publication ID

2342797

0 references

1 reference

16 February 2018