(Q48873582)

English

L-AP4 (L-(+)-2-amino-4-phosphonobutyric acid) induced impairment of spatial learning in the rat is antagonized by MAP4 ((S)-2-amino-2-methyl-4-phosphonobutanoic acid).

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scholarly article

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

L-AP4 (L-(+)-2-amino-4-phosphonobutyric acid) induced impairment of spatial learning in the rat is antagonized by MAP4 ((S)-2-amino-2-methyl-4-phosphonobutanoic acid). (English)

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

1 reference

ChEBI release 2020-05-28

Christian Hölscher

1

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

author name string

McGlinchey L

2

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

Rowan MJ

3

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

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publication date

1 November 1996

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

Behavioural Brain Research

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

81

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

69-79

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

1-2

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

Activation of AP5-sensitive NMDA Receptors is Not Required to Induce LTP of Synaptic Transmission in the Lateral Perforant Path

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Antagonism of the synaptic depressant actions of L-AP4 in the lateral perforant path by MAP4

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Positive feedback of glutamate exocytosis by metabotropic presynaptic receptor stimulation

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Micromolar L-2-amino-4-phosphonobutyric acid selectively inhibits perforant path synapses from lateral entorhinal cortex

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Activity of the conformationally rigid 2-amino-4-phosphonobutanoic acid (AP4) analogue (RS)-1-amino-3-(phosphonomethylene)cyclobutane-1-carboxyclic acid (cyclobutylene AP5) on evoked responses in the perforant pathway of rat hippocampus

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Evidence for presynaptic depression of monosynaptic excitation in neonatal rat motoneurones by (1S,3S)- and (1S,3R)-ACPD

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Trans-ACPD and L-APB presynaptically inhibit excitatory glutamatergic transmission in the basolateral amygdala (BLA).

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Activation of metabotropic glutamate receptors is necessary for long-term potentiation in the dentate gyrus and for spatial learning.

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(R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) blocks spatial learning in rats and long-term potentiation in the dentate gyrus in vivo.

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Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG

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Distinct presynaptic metabotropic receptors for L-AP4 and CCG1 on GABAergic terminals: pharmacological evidence using novel alpha-methyl derivative mGluR antagonists, MAP4 and MCCG, in the rat thalamus in vivo

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Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4.

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L-AP4 inhibits calcium currents and synaptic transmission via a G- protein-coupled glutamate receptor

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Identifiers

10.1016/S0166-4328(96)00045-9

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/8950003

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