(Q48886286)

English

Forskolin modulates acetylcholine receptor gating by interacting with the small extracellular loop between the M2 and M3 transmembrane domains.

scientific article published in October 2000

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scholarly article

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

Forskolin modulates acetylcholine receptor gating by interacting with the small extracellular loop between the M2 and M3 transmembrane domains. (English)

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

transmembrane protein

0 references

author name string

Z Chen

1

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

M M White

2

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

publication date

1 October 2000

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

Cellular and Molecular Neurobiology

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

20

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

5

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

569-577

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

https://scigraph.springernature.com/pub.10.1023/a:1007011911611

0 references

Voltage jump analysis of procaine action at frog end-plate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short chain and long chain alkanols have different sites of action on nicotinic acetylcholine receptor channels from Torpedo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local anesthetics and histrionicotoxin are allosteric inhibitors of the acetylcholine receptor. Studies of clonal muscle cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forskolin alters acetylcholine receptor gating by a mechanism independent of adenylate cyclase activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The noncompetitive blocker [3H]chlorpromazine labels three amino acids of the acetylcholine receptor gamma subunit: implications for the alpha-helical organization of regions MII and for the structure of the ion channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of acetylcholine receptor desensitization by forskolin is independent of cAMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forskolin acts as a noncompetitive inhibitor of nicotinic acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

d-Tubocurarine binding sites are located at alpha-gamma and alpha-delta subunit interfaces of the nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of Torpedo acetylcholine receptor biosynthesis in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Startle disease mutations reduce the agonist sensitivity of the human inhibitory glycine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local anaesthetics transiently block currents through single acetylcholine-receptor channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective enhancement of the interaction of curare with the nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of noncompetitive inhibition of acetylcholine-induced single-channel currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenesis of the GABA rho 1 receptor alters agonist affinity and channel gating

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the alpha-subunit site photolabeled by the noncompetitive inhibitor [3H]quinacrine azide in the active state of the nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct anesthetic-like effects of forskolin on the nicotinic acetylcholine receptors of PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An analog of lophotoxin reacts covalently with Tyr190 in the alpha-subunit of the nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The multiple phenotypes of allosteric receptor mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of amino acids contributing to high and low affinity d-tubocurarine sites in the Torpedo nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-induced changes in the structure of the acetylcholine receptor M2 regions revealed by photoincorporation of an uncharged nicotinic noncompetitive antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A residue in the middle of the M2-M3 loop of the beta4 subunit specifically affects gating of neuronal nicotinic receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of adenylate cyclase by water-soluble analogues of forskolin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of chlorpromazine and phencyclidine on mouse C2 acetylcholine receptor kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1007011911611

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/10930133

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