(Q48886401)

16 February 2018

title

P2RX7 gene is associated consistently with mood disorders and predicts clinical outcome in three clinical cohorts. (English)

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16 February 2018

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2

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16 February 2018

Jari Haukka

12

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16 February 2018

Erkki T Isometsä

13

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16 February 2018

author name string

Pia Soronen

1

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16 February 2018

Tarja Melartin

3

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16 February 2018

Kirsi Suominen

4

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16 February 2018

Maria Vuorilehto

5

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16 February 2018

Heikki Rytsälä

6

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16 February 2018

Petri Arvilommi

7

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16 February 2018

Irina Holma

8

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16 February 2018

Mikael Holma

9

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16 February 2018

Pekka Jylhä

10

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16 February 2018

Hanna M Valtonen

11

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16 February 2018

Tiina Paunio

14

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16 February 2018

publication date

22 March 2011

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16 February 2018

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

published in

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16 February 2018

volume

156B

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16 February 2018

issue

4

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16 February 2018

page(s)

435-447

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16 February 2018

Extensive genotyping of the BDNF and NTRK2 genes define protective haplotypes against obsessive-compulsive disorder.

cites work

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Diagnostic conversion from depression to bipolar disorders: results of a long-term prospective study of hospital admissions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of the serotonin transporter promoter polymorphism with suicidal behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

The 5-HTTLPR s/s genotype at the serotonin transporter gene (SLC6A4) increases the risk for depression in a large cohort of primary care attendees: the PREDICT-gene study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: a systematic review and meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5'-region are associated with bipolar affective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

MAOA-uVNTR polymorphism in a Brazilian sample: further support for the association with impulsive behaviors and alcohol dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Variation in brain-derived neurotrophic factor (BDNF) gene is associated with symptoms of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Population-based study of first onset and chronicity in major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Meta-analysis of the association between the monoamine oxidase-A gene and mood disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Meta-analysis of the association of a functional serotonin transporter promoter polymorphism with alcohol dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Meta-analysis of the brain-derived neurotrophic factor gene (BDNF) Val66Met polymorphism in anxiety disorders and anxiety-related personality traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

P2RX7: A bipolar and unipolar disorder candidate susceptibility gene?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Variation in P2RX7 candidate gene (rs2230912) is not associated with bipolar I disorder and unipolar major depression in four European samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association analysis between a functional polymorphism in the monoamine oxidase A gene promoter and severe mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Variation in DISC1 is associated with anxiety, depression and emotional stability in elderly women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Polymorphisms in the neuronal isoform of tryptophan hydroxylase 2 are associated with bipolar disorder in French Canadian pedigrees.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Polymorphisms at the G72/G30 gene locus, on 13q33, are associated with bipolar disorder in two independent pedigree series

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association analysis of the insertion/deletion polymorphism in serotonin transporter gene in patients with affective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association between depression and the Gln460Arg polymorphism of P2RX7 gene: a dimensional approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

What is the genetic relationship between anxiety and depression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Catechol-O-methyltransferase contributes to genetic susceptibility shared among anxiety spectrum phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

The power of sample size and homogenous sampling: association between the 5-HTTLPR serotonin transporter polymorphism and major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Long-Term Outcome of Major Depressive Disorder in Psychiatric Patients Is Variable

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Serotonin transporter gene promoter (5-HTTLPR) and intron 2 (VNTR) polymorphisms in Croatian suicide victims

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of monoamine oxidase A alleles with alcoholism among male Chinese in Taiwan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with psychotic feature and suicidal behavior in Japanese major depressive patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Meta-analyses suggest association between COMT, but not HTR1B, alleles, and suicidal behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

High Concordance of Bipolar I Disorder in a Nationwide Sample of Twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Brain-derived neurotrophic factor Val/Met polymorphism and bipolar disorder. Association of the Met allele with suicidal behavior of bipolar patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association between serotonin transporter gene promoter polymorphism and suicide: results of a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Overview of the genetics of major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Confirmation of association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and bipolar I disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Meta-analyses of genetic studies on major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

STin2 variant and family history of suicide as significant predictors of suicide completion in major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Meta-analysis of serotonin transporter polymorphisms and affective disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Candidate endophenotypes for genetic studies of suicidal behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

The clinical characteristics of DSM-IV bipolar I and II disorders: baseline findings from the Jorvi Bipolar Study (JoBS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Differences in outcome of DSM-IV bipolar I and II disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association between COMT (Val158Met) functional polymorphism and early onset in patients with major depressive disorder in a European multicenter genetic association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association between catechol-O-methyltransferase and phobic anxiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

The Heritability of Bipolar Affective Disorder and the Genetic Relationship to Unipolar Depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Case-control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Current Comorbidity of Psychiatric Disorders Among DSM-IV Major Depressive Disorder Patients in Psychiatric Care in the Vantaa Depression Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

The BDNF Val66Met polymorphism and anxiety: support for animal knock-in studies from a genetic association study in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Further evidence of MAO-A gene variants associated with bipolar disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association study of a functional catechol-O-methyltransferase (COMT) Val108/158Met polymorphism and suicide attempts in patients with alcohol dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Is the 5-HTTLPR polymorphism associated with bipolar disorder or with suicidal behavior of bipolar disorder patients?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Polymorphism in serotonin transporter gene associated with susceptibility to major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association between catechol-O-methyltransferase functional polymorphism and male suicide completers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association and linkage of anxiety-related traits with a functional polymorphism of the serotonin transporter gene regulatory region in Israeli sibling pairs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Clinical features of bipolar depression versus major depressive disorder in large multicenter trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

DSM-IV mood-, anxiety- and alcohol use disorders and their comorbidity in the Finnish general population--results from the Health 2000 Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of DAO and G72(DAOA)/G30 genes with bipolar affective disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Sex-specific genetic influences on the comorbidity of alcoholism and major depression in a population-based sample of US twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association between suicide attempts and 5-HTTLPR-S-allele in alcohol-dependent and control subjects: further evidence from a German alcohol-dependent inpatient sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

PLINK: a tool set for whole-genome association and population-based linkage analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

The brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

G72 and its association with major depression and neuroticism in large population-based groups from Germany.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

High-activity variants of the uMAOA polymorphism increase the risk for depression in a large primary care sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Support for tryptophan hydroxylase-2 as a susceptibility gene for bipolar affective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

A functional polymorphism in the monoamine oxidase A gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

A meta-analysis of the association between the serotonin transporter gene polymorphism (5-HTTLPR) and trait anxiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of DISC1 and TSNAX genes and affective disorders in the depression case-control (DeCC) and bipolar affective case-control (BACCS) studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Examination of G72 and D-amino-acid oxidase as genetic risk factors for schizophrenia and bipolar affective disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

COMT: a common susceptibility gene in bipolar disorder and schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Genome-wide association study of bipolar disorder in European American and African American individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Genetic epidemiology of major depression: review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of variants in DISC1 with psychosis-related traits in a large population cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Tryptophan hydroxylase 2 gene is associated with major depression and antidepressant treatment response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association of brain-specific tryptophan hydroxylase, TPH2, with unipolar and bipolar disorder in a Northern Swedish, isolated population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Depressive disorders in primary care: recurrent, chronic, and co-morbid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Course and outcome of depressive disorders in primary care: a prospective 18-month study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Nucleotide sequence variation within the human tyrosine kinase B neurotrophin receptor gene: association with antisocial alcohol dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Single nucleotide polymorphism and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene in suicide victims

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Evidence for a genetic association between alleles of monoamine oxidase a gene and bipolar affective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Excess of High Activity Monoamine Oxidase A Gene Promoter Alleles in Female Patients with Panic Disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

Association Between Bipolar Disorder and Monoamine Oxidase A Gene Polymorphisms: Results of a Multicenter Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.31179

21 January 2018

Identifiers

DOI

10.1002/AJMG.B.31179

1 reference

16 February 2018

PubMed ID

21438144

1 reference

16 February 2018