(Q48910156)

16 February 2018

title

Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors. (English)

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16 February 2018

author name string

M Legraverend

1

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16 February 2018

O Ludwig

2

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16 February 2018

E Bisagni

3

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16 February 2018

S Leclerc

4

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16 February 2018

L Meijer

5

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16 February 2018

N Giocanti

6

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16 February 2018

R Sadri

7

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16 February 2018

V Favaudon

8

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16 February 2018

language of work or name

English

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publication date

1 July 1999

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16 February 2018

Bioorganic & Medicinal Chemistry

published in

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16 February 2018

volume

7

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16 February 2018

issue

7

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16 February 2018

page(s)

1281-1293

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16 February 2018

Role of cyclin-dependent kinases and their inhibitors in cellular differentiation and development

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Aberrations of the G1- and G1/S-regulating genes in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Chemical inhibitors of cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Inhibition of cyclin-dependent kinases by purine analogues.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Induction of apoptosis and regression of spontaneous dog melanoma following in vivo application of synthetic cyclin-dependent kinase inhibitor olomoucine

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Apoptosis of central and peripheral neurons can be prevented with cyclin-dependent kinase/mitogen-activated protein kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Inhibition of cellular Cdk2 activity blocks human cytomegalovirus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Early inhibition of DNA synthesis in the developing rat cerebral cortex by the purine analogues olomoucine and roscovitine.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Facile Preparation of 2,6-Disubstituted Purines Using Solid-Phase Chemistry

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Modification of Nucleic Acid Bases via Radical Intermediates: Synthesis of Dihalogenated Purine Nucleosides

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Nucleosides and nucleotides. 103. 2-Alkynyladenosines: a novel class of selective adenosine A2 receptor agonists with potent antihypertensive effects

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Association of neurofilament proteins with neuronal Cdk5 activator.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Effects of olomoucine, a selective inhibitor of cyclin-dependent kinases, on cell cycle progression in human cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Olomoucine, an inhibitor of the cdc2/cdk2 kinases activity, blocks plant cells at the G1 to S and G2 to M cell cycle transitions

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Roscovitine, a novel cyclin-dependent kinase inhibitor, characterizes restriction point and G2/M transition in tobacco BY-2 cell suspension.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

The effect of the cyclin-dependent kinase inhibitor olomoucine on cell cycle kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Cell cycle-independent induction of apoptosis by the anti-tumor drug Flavopiridol in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Kinase and phosphatase inhibitors cause rapid alterations in microtubule dynamic instability in living cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Reversal of terminal differentiation and control of DNA replication: cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Localization of Cyclin A at the Sites of Cellular DNA Replication

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Role for cyclin A-dependent kinase in DNA replication in human S phase cell extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Variations in several responses of HeLa cells to x-irradiation during the division cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

X-ray sensitivity during the cell generation cycle of cultured Chinese hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Cell-cycle-stage specificity of 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) and interaction with ionizing radiation in mammalian cell cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Substructure in the radiation survival response at low dose: asynchronous and partially synchronized V79-WNRE cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Computer programs for the analysis of cellular survival data.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

BrdUrd/DNA flow cytometry analysis demonstrates cis-diamminedichloroplatinum (II)-induced multiple cell-cycle modifications on human lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

Average versus Viable Cell Multiplicity in Survival Determination for Mammalian Cells in Vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900064-4

7 January 2021

10.1016/S0968-0896(99)00064-4

Identifiers

DOI

1 reference

16 February 2018

1 reference

16 February 2018