(Q48910607)

English

Prodrugs of peptides. 6. Bioreversible derivatives of thyrotropin-releasing hormone (TRH) with increased lipophilicity and resistance to cleavage by the TRH-specific serum enzyme.

scientific article published in September 1990

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

Prodrugs of peptides. 6. Bioreversible derivatives of thyrotropin-releasing hormone (TRH) with increased lipophilicity and resistance to cleavage by the TRH-specific serum enzyme. (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

author name string

H Bundgaard

1

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

J Møss

2

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

publication date

1 September 1990

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

7

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

9

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

885-892

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

Imidazole catalysis. II. Acyl transfer and the reactions of acetyl imidazole with water and oxygen anions

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of thyrotropin-releasing hormone with analogs: influence of disposition upon pharmacology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a pyroglutamate aminopeptidase from rat serum that degrades thyrotropin-releasing hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orientation restrictions of the peptide hormone, thyrotropin-releasing factor, due to intramolecular hydrogen bonding

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pilocarpine prodrugs. II. Synthesis, stability, bioconversion, and physicochemical properties of sequentially labile pilocarpine acid diesters

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics and pattern of degradation of thyrotropin-releasing hormone (TRH) in human plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a Thyroliberin-Degrading Serum Enzyme Catalyzing the Hydrolysis of Thyroliberin at the Pyroglutamyl-Histidine Bond

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Pharmacokinetics and pharmacodynamics of protirelin (TRH) in man]

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethoxyformylation of proteins. Reaction of ethoxyformic anhydride with .alpha.-chymotrypsin, pepsin, and pancreatic ribonuclease at pH 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory peptides as a source of new drugs--the clinical prospects for analogues of TRH which are resistant to metabolic degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyroglutamic acid. Non-metabolic formation, function in proteins and peptides, and characteristics of the enzymes effecting its removal

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of a Serum Peptidase Hydrolyzing Thyroliberin at the Pyroglutamyl-Histidine Bond

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptides and the blood-brain barrier: lipophilicity as a predictor of permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prodrugs of peptides. IV: Bioreversible derivatization of the pyroglutamyl group by N-acylation and N-aminomethylation to effect protection against pyroglutamyl aminopeptidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropeptide-specific peptidases: does brain contain a specific TRH-degrading enzyme?

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal absorption mechanisms of thyrotropin-releasing hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood level and brain distribution of thyrotropin-releasing hormone (TRH) determined by radioimmunoassay after intravenous administration in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absorption of thyrotropin-releasing hormone after oral administration of TRH tartrate monohydrate in the rat, dog and human.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prodrug derivatives of thyrotropin-releasing hormone and other peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and excretion of exogenous thyrotropin-releasing hormone in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra- and extravascular turnover of thyrotrophin-releasing hormone in normal man

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary thyrotropin-releasing hormone-degrading enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyrotropin-releasing hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delineation of a particulate thyrotropin-releasing hormone-degrading enzyme in rat brain by the use of specific inhibitors of prolyl endopeptidase and pyroglutamyl peptide hydrolase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma Clearance and Plasma Half-Disappearance Time of Exogenous Thyrotropin-Releasing Hormone and Pyroglutamyl-N3im-Methyl-Histidyl Prolineamide*

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoreactivity and Serum Destruction of N3imMethyl-TRH

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical applications of thyrotrophin-releasing hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation and biological inactivation of thyrotropin releasing hormone (TRH): regulation of the membrane-bound TRH-degrading enzyme from rat anterior pituitary by estrogens and thyroid hormones

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of thyrotropin-releasing hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of TRH-degrading enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyrotrophin releasing hormone: endocrine and central effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyrotrophin-releasing hormone. New applications in the clinic

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simplified high-pressure liquid chromatography method for determining lipophilicity for structure-activity relationships.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2122435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1015933504191

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/2122435

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