(Q48913312)

16 February 2018

title

Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor (English)

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16 February 2018

author name string

Choi YB

series ordinal

1

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16 February 2018

Lipton SA

series ordinal

2

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16 February 2018

language of work or name

English

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publication date

1 May 1999

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16 February 2018

published in

Neuron

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16 February 2018

volume

23

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16 February 2018

issue

1

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16 February 2018

page(s)

171-180

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16 February 2018

Release of endogenous Zn2+ from brain tissue during activity

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Differential sensitivity of recombinant N-methyl-D-aspartate receptor subtypes to zinc inhibition

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Modulation of pH by neuronal activity

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Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons

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Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C

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The role of an alpha subtype M2-M3 His in regulating inhibition of GABAA receptor current by zinc and other divalent cations

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Zinc potentiates agonist-lnduced currents at certain splice variants of the NMDA receptor

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N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1.

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The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge

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Stimulation-induced uptake and release of zinc in hippocampal slices

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Neuroprotective effects of glutamate antagonists and extracellular acidity

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Zinc alters excitatory amino acid neurotoxicity on cortical neurons

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The role of zinc in selective neuronal death after transient global cerebral ischemia

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Molecular diversity of the NMDA receptor channel

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The inhibition of single N-methyl-D-aspartate-activated channels by zinc ions on cultured rat neurones

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Apparent desensitization of NMDA responses in xenopus oocytes involves calcium-dependent chloride current

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Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.

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The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B).

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Identification by mutagenesis of a Mg(2+)-block site of the NMDA receptor channel

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Molecular cloning and characterization of the rat NMDA receptor

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7 January 2021

High-Affinity Zinc Inhibition of NMDA NR1–NR2A Receptors

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7 January 2021

Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons

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7 January 2021

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

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7 January 2021

Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc

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7 January 2021

Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing

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7 January 2021

Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor

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7 January 2021

Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines

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7 January 2021

Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit.

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7 January 2021

The biochemical basis of zinc physiology

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7 January 2021

A single histidine residue is essential for zinc inhibition of GABA rho 1 receptors

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7 January 2021

Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons

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7 January 2021

Separating dual effects of zinc at recombinant N-methyl-D-aspartate receptors

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7 January 2021

Transmembrane topology of two kainate receptor subunits revealed by N-glycosylation

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7 January 2021

Structural conservation of ion conduction pathways in K channels and glutamate receptors

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7 January 2021

Identification of a Zn2+ binding site on the murine GABAA receptor complex: dependence on the second transmembrane domain of beta subunits.

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7 January 2021

A physiological role for endogenous zinc in rat hippocampal synaptic neurotransmission

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7 January 2021

Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition

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7 January 2021

10.1016/S0896-6273(00)80763-1

Identifiers

DOI

1 reference

16 February 2018

1 reference

16 February 2018