(Q48921248)

16 February 2018

title

The effects of a point mutation of the beta2 subunit of GABA(A) receptor on direct and modulatory actions of general anesthetics. (English)

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16 February 2018

author name string

Fukami S

1

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16 February 2018

Uchida I

2

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16 February 2018

Takenoshita M

3

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16 February 2018

Mashimo T

4

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16 February 2018

Yoshiya I

5

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16 February 2018

language of work or name

English

0 references

publication date

1 March 1999

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16 February 2018

European Journal of Pharmacology

published in

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16 February 2018

volume

368

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16 February 2018

issue

2-3

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16 February 2018

page(s)

269-276

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16 February 2018

GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital.

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900033-3

The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid

7 January 2021

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A Structural Determinant of Desensitization and Allosteric Regulation by Pentobarbitone of the GABA A Receptor

7 January 2021

1 reference

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A point mutation in the gamma2 subunit of gamma-aminobutyric acid type A receptors results in altered benzodiazepine binding site specificity

7 January 2021

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Stoichiometry of a recombinant GABAA receptor.

7 January 2021

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Modulation by general anaesthetics of rat GABAA receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells.

7 January 2021

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Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit

7 January 2021

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Molecular and cellular mechanisms of general anaesthesia

7 January 2021

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Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor

7 January 2021

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The effects of general anaesthetics on GABAergic synaptic transmission

7 January 2021

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Alpha subunit isoform influences GABA(A) receptor modulation by propofol

7 January 2021

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Direct evidence for diazepam modulation of GABAA receptor microscopic affinity.

7 January 2021

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GABAA/benzodiazepine receptor heterogeneity: neurophysiological implications.

7 January 2021

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7 January 2021

GABAA receptor channels

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The pharmacology of the benzodiazepine site of the GABA-A receptor is dependent on the type of gamma-subunit present

7 January 2021

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Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

7 January 2021

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Propofol modulates activation and desensitization of GABAA receptors in cultured murine hippocampal neurons.

7 January 2021

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The role of the GABAA receptor/chloride channel complex in anesthesia.

7 January 2021

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Barbiturate interactions at the human GABAA receptor: dependence on receptor subunit combination

7 January 2021

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The differential antagonism by bicuculline and SR95531 of pentobarbitone-induced currents in cultured hippocampal neurons.

7 January 2021

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The role of the GABA(A) receptor alpha1 subunit N-terminal extracellular domain in propofol potentiation of chloride current.

7 January 2021

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Functional properties of recombinant rat GABAA receptors depend upon subunit composition

7 January 2021

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A novel gamma-aminobutyric acid receptor subunit (rho 2) cloned from human retina forms bicuculline-insensitive homooligomeric receptors in Xenopus oocytes

7 January 2021

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The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit

7 January 2021

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Two tyrosine residues on the alpha subunit are crucial for benzodiazepine binding and allosteric modulation of gamma-aminobutyric acidA receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900033-3

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-2999(99)00033-3

1 reference

16 February 2018

PubMed ID

10193664

1 reference

16 February 2018