(Q48921606)

16 February 2018

title

Injury-induced apoptosis of neurons in adult brain is mediated by p53-dependent and p53-independent pathways and requires Bax. (English)

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16 February 2018

author name string

Martin LJ

1

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16 February 2018

Kaiser A

2

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16 February 2018

Yu JW

3

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16 February 2018

Natale JE

4

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16 February 2018

Al-Abdulla NA

5

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16 February 2018

language of work or name

English

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publication date

1 May 2001

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16 February 2018

The Journal of Comparative Neurology

published in

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16 February 2018

volume

433

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16 February 2018

page(s)

299-311

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16 February 2018

issue

3

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16 February 2018

Axotomy-induced neuronal death and reactive astrogliosis in the lateral geniculate nucleus following a lesion of the visual cortex in the rat.

cites work

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Apoptosis of retrogradely degenerating neurons occurs in association with the accumulation of perikaryal mitochondria and oxidative damage to the nucleus

21 January 2018

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Occipital cortex ablation in adult rat causes retrograde neuronal death in the lateral geniculate nucleus that resembles apoptosis.

21 January 2018

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Inhibition of Bax channel-forming activity by Bcl-2

21 January 2018

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Comparative evaluation of synaptophysin-based methods for quantification of synapses

21 January 2018

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BAX is required for neuronal death after trophic factor deprivation and during development

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Comparative analysis of p73 and p53 regulation and effector functions

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Alzheimer's disease: neurofibrillary tangles in nuclei that project to the cerebral cortex.

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Differential requirement for caspase 9 in apoptotic pathways in vivo.

21 January 2018

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Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus

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Apoptotic cell death in neurons and glial cells: implications for Alzheimer's disease

21 January 2018

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

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Identification and characterization of a spinal muscular atrophy-determining gene

21 January 2018

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p53, the cellular gatekeeper for growth and division

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

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Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy

21 January 2018

1 reference

Detection of higher-order 50- and 10-kbp DNA fragments before apoptotic internucleosomal cleavage after transient cerebral ischemia.

21 January 2018

1 reference

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

21 January 2018

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p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis.

21 January 2018

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Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis.

21 January 2018

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Bcl-2 gene family in the nervous system

21 January 2018

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p63 is a p53 homologue required for limb and epidermal morphogenesis

21 January 2018

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Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

21 January 2018

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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Expression of bcl-2, bax, and caspase-3 in the brain of the developing rat.

21 January 2018

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Cell death during development of the nervous system

21 January 2018

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A model for p53-induced apoptosis

21 January 2018

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The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

21 January 2018

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Neuronal pathology in the nucleus basalis and associated cell groups in senile dementia of the Alzheimer's type: possible role in cell loss

21 January 2018

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p53 function and dysfunction

21 January 2018

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Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

21 January 2018

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

1 reference

21 January 2018

DNA damage enables p73

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The neuropathology of the vegetative state after an acute brain insult

21 January 2018

1 reference

Attenuation of p53 expression protects against focal ischemic damage in transgenic mice

21 January 2018

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Cell deaths in normal vertebrate ontogeny

21 January 2018

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Activation of caspase-3 in axotomized rat retinal ganglion cells in vivo

21 January 2018

1 reference

Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis

21 January 2018

1 reference

Apoptosis and necrosis occur in separate neuronal populations in hippocampus and cerebellum after ischemia and are associated with differential alterations in metabotropic glutamate receptor signaling pathways

21 January 2018

1 reference

The neuroanatomy of Alzheimer's disease

21 January 2018

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p53-deficient mice are protected against adrenalectomy-induced apoptosis.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/CNE.1141

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16 February 2018

PubMed ID

11298357

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16 February 2018