(Q48925736)

16 February 2018

title

Steady-state kinetics of imipramine in transgenic mice with elevated serum AAG levels. (English)

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16 February 2018

author name string

J W Holladay

series ordinal

1

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16 February 2018

M J Dewey

series ordinal

2

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16 February 2018

S D Yoo

series ordinal

3

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16 February 2018

publication date

1 September 1996

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16 February 2018

published in

Pharmaceutical Research

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16 February 2018

volume

13

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16 February 2018

issue

9

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16 February 2018

page(s)

1313-1316

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16 February 2018

Rapid microsample analysis of imipramine and desipramine by reversed-phase high-performance liquid chromatography with ultraviolet detection

cites work

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12 December 2020

Measurement and pharmacokinetic analysis of imipramine and its metabolite by brain microdialysis

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12 December 2020

Effects of the binding of imipramine to erythrocytes and plasma proteins on its transport through the rat blood-brain barrier.

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12 December 2020

Importance of protein binding for the interpretation of serum or plasma drug concentrations

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12 December 2020

A quantitative study in the rat on the relationship between imipramine levels in brain and serum.

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12 December 2020

Chronic administration of phencyclidine: pharmacokinetic comparison of intravenous and subcutaneous infusions in Sprague-Dawley rats

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12 December 2020

Elevated plasma concentrations of alpha 1-acid glycoprotein, a putative endogenous inhibitor of the tritiated imipramine binding site, in depressed patients

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12 December 2020

Increased alpha-1-acid glycoprotein in depression lowers free fraction of imipramine

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12 December 2020

Altered disposition and antidepressant activity of imipramine in transgenic mice with elevated alpha-1-acid glycoprotein

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12 December 2020

Regional distribution of imipramine, desipramine and specific [3H]desipramine binding sites in the rat brain after acute and chronic treatment with imipramine.

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12 December 2020

Cerebral and blood pharmacokinetics of imipramine and its active metabolites in the pregnant rat

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12 December 2020

Nonlinear kinetics of imipramine in low and medium plasma level ranges.

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12 December 2020

First-pass metabolism of imipramine and desipramine: Impact of the sparteine oxidation phenotype

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12 December 2020

Decreased elimination of drug in the presence of alpha-1-acid glycoprotein is related to a reduced hepatocyte uptake

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12 December 2020

Quantification of imipramine and its major metabolites in whole blood, brain, and other tissues of the rat by liquid chromatography

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12 December 2020

Inducible and tissue-specific expression of rat alpha-1-acid glycoprotein in transgenic mice

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12 December 2020

Binding of chlorpromazine and imipramine to red cells, albumin, lipoproteins and other blood components

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12 December 2020

Identifiers

DOI

10.1023/A:1016005529420

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16 February 2018

PubMed ID

8893267

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16 February 2018