(Q48955259)

17 February 2018

title

Strategy to assess the role of (inter)active metabolites in pharmacodynamic studies in-vivo: a model study with heptabarbital. (English)

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17 February 2018

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Dingemanse J

1

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17 February 2018

Thomassen D

series ordinal

2

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17 February 2018

Mentink BH

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3

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17 February 2018

Danhof M

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4

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17 February 2018

publication date

1 August 1988

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17 February 2018

Journal of Pharmacy and Pharmacology

published in

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17 February 2018

volume

40

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17 February 2018

issue

8

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17 February 2018

page(s)

552-557

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17 February 2018

Effect of active drug metabolites on plasma level-response correlations

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1988.TB05301.X

Pharmacokinetics of the enantiomers of hexobarbital studied in the same intact rat and in the same isolated perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1988.TB05301.X

Stereochemical dependence of pharmacological activity in a series of optically active N-methylated barbiturates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1988.TB05301.X

Pharmacokinetic-pharmacodynamic modeling of CNS drug effects: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1988.TB05301.X

Pharmacological comparison of R(+), S(-) and racemic secobarbital in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1988.TB05301.X

Barbiturate receptor sites are coupled to benzodiazepine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1988.TB05301.X

Diurnal variation in sensitivity to and metabolism of barbiturate in the rat: Lack of correlation between in vivo and in vitro findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1988.TB05301.X

The antagonistic effects of 5-ethyl-5-(3-hydroxy-1-methylbutyl)-barbituric acid on pentobarbital narcosis in both naïve and tolerant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1988.TB05301.X

10.1111/J.2042-7158.1988.TB05301.X

21 January 2018

Identifiers

DOI

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17 February 2018

1 reference

17 February 2018