(Q49031725)

17 February 2018

title

Divergent phosphorylation pattern of tau in P301L tau transgenic mice. (English)

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17 February 2018

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2

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Jürgen Götz

series ordinal

3

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17 February 2018

author name string

Natasha Deters

series ordinal

1

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17 February 2018

language of work or name

English

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publication date

1 July 2008

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17 February 2018

European Journal of Neuroscience

published in

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17 February 2018

volume

28

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page(s)

137-147

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17 February 2018

issue

1

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17 February 2018

The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease

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Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.

21 January 2018

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Regional Distribution of Neurofibrillary Tangles and Senile Plaques in the Cerebral Cortex of Elderly Patients: A Quantitative Evaluation of a One-Year Autopsy Population from a Geriatric Hospital

21 January 2018

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A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads.

21 January 2018

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Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Phosphorylated serine422 on tau proteins is a pathological epitope found in several diseases with neurofibrillary degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Posttranslational modifications of tau--role in human tauopathies and modeling in transgenic animals

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Role for glyoxalase I in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Beta-amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

The neuronal microtubule-associated protein tau is a substrate for caspase-3 and an effector of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

beta-Amyloid induces paired helical filament-like tau filaments in tissue culture

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Molecular dissection of the paired helical filament

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Tau filament formation in transgenic mice expressing P301L tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

A decade of tau transgenic animal models and beyond

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Pronuclear injection for the production of transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Kinase activities increase during the development of tauopathy in htau mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Active immunization trial in Abeta42-injected P301L tau transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Neurodegenerative tauopathies: human disease and transgenic mouse models

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Neurodegenerative tauopathies

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Transgenic animal models of tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Different tau epitopes define Abeta42-mediated tau insolubility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Tau suppression in a neurodegenerative mouse model improves memory function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

In vitro tau fibrillization: mapping protein regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Tau phosphorylation sites work in concert to promote neurotoxicity in vivo

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

Tau and transgenic animal models

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06318.X

10.1111/J.1460-9568.2008.06318.X

21 January 2018

Identifiers

DOI

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17 February 2018

PubMed ID

18662339

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17 February 2018