(Q49051354)

18 February 2018

title

Deguelin inhibits expression of IkappaBalpha protein and induces apoptosis of B-CLL cells in vitro. (English)

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18 February 2018

B-cell chronic lymphocytic leukemia

main subject

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6

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18 February 2018

author name string

B Geeraerts

1

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18 February 2018

B Vanhoecke

2

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18 February 2018

W Vanden Berghe

3

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18 February 2018

J Philippé

4

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18 February 2018

F Offner

5

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18 February 2018

publication date

14 June 2007

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18 February 2018

published in

Leukemia

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18 February 2018

volume

21

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18 February 2018

issue

8

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18 February 2018

page(s)

1610-1618

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18 February 2018

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404788

exact match

0 references

cites work

Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance

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Cancer chemopreventive activity of rotenoids from Derris trifoliata

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7 January 2021

Natural inhibitors of carcinogenesis

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7 January 2021

Regulating expressions of cyclin D1, pRb, and anti-cancer effects of deguelin on human Burkitt's lymphoma Daudi cells in vitro

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7 January 2021

Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest

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7 January 2021

Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis.

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7 January 2021

Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice

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7 January 2021

Molecular mechanisms of deguelin-induced apoptosis in transformed human bronchial epithelial cells

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AKT and the phosphatidylinositol 3-kinase/AKT pathway: important molecular targets for lung cancer prevention and treatment

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7 January 2021

Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells

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Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway

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7 January 2021

Deguelin inhibits expression of IkappaBalpha protein in Raji and U937 cells

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7 January 2021

Genetics and molecular biology of chronic lymphocytic leukemia

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7 January 2021

Chronic lymphocytic leukemia

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7 January 2021

B-cell chronic lymphocytic leukemia: a bird of a different feather

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7 January 2021

Bodyguards and assassins: Bcl-2 family proteins and apoptosis control in chronic lymphocytic leukaemia.

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7 January 2021

Survival role of protein kinase C (PKC) in chronic lymphocytic leukemia and determination of isoform expression pattern and genes altered by PKC inhibition

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7 January 2021

ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

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7 January 2021

The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells

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7 January 2021

A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.

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7 January 2021

Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells

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7 January 2021

BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway

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7 January 2021

ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

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7 January 2021

Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium

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7 January 2021

Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia

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7 January 2021

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

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7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

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7 January 2021

Mcl-1 and Bcl-2/Bax ratio are associated with treatment response but not with Rai stage in B-cell chronic lymphocytic leukemia

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7 January 2021

Involvement of protein kinase C and phosphatidylinositol 3-kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells.

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7 January 2021

Expression profile of 11 proteins and their prognostic significance in patients with chronic lymphocytic leukemia (CLL).

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7 January 2021

KRN5500: a novel therapeutic agent with in vitro activity against human B-cell chronic lymphocytic leukemia cells mediates cytotoxicity via the intrinsic pathway of apoptosis

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7 January 2021

VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance

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7 January 2021

CDDO induces apoptosis via the intrinsic pathway in lymphoid cells.

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7 January 2021

STAT1 mediates differentiation of chronic lymphocytic leukemia cells in response to Bryostatin 1.

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7 January 2021

Clinical effects of oral green tea extracts in four patients with low grade B-cell malignancies

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7 January 2021

Dysregulation of apoptosis genes in hematopoietic malignancies.

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7 January 2021

MCL-1 promoter insertions dial-up aggressiveness of chronic leukemia

1 reference

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7 January 2021

Flavopiridol administered as a 24-hour continuous infusion in chronic lymphocytic leukemia lacks clinical activity

1 reference

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7 January 2021

Autologous plasma activates Akt/protein kinase B and enhances basal survival and resistance to DNA damage-induced apoptosis in B-chronic lymphocytic leukaemia cells

1 reference

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7 January 2021

Protection from apoptotic cell death by interleukin-4 is increased in previously treated chronic lymphocytic leukemia patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404788

7 January 2021

Pharmacokinetics of deguelin, a cancer chemopreventive agent in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404788

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2404788

1 reference

18 February 2018

Dimensions Publication ID

0 references

1 reference

18 February 2018