(Q49084771)

English

Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety.

scientific article published in April 2000

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scholarly article

1 reference

Europe PubMed Central

18 February 2018

http://europepmc.org/abstract/MED/10751426

Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

0 references

author name string

E Sibille

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

C Pavlides

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

D Benke

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

M Toth

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 April 2000

1 reference

Europe PubMed Central

18 February 2018

http://europepmc.org/abstract/MED/10751426

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

20

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

2758-2765

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic intermittent ethanol treatment in rats increases GABA(A) receptor alpha4-subunit expression: possible relevance to alcohol dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional GABAA receptors on rat vagal afferent neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin depresses excitatory synaptic transmission and depolarization-evoked Ca2+ influx in rat basolateral amygdala via 5-HT1A receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased benzodiazepine receptor binding in panic disorder measured by IOMAZENIL-SPECT. A preliminary report.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAergic antagonists block the inhibitory effects of serotonin in the lateral amygdala: a mechanism for modulation of sensory inputs related to fear conditioning.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1A receptor agonists: recent developments and controversial issues

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of central nervous 5-HT1A-receptors under psychosocial stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAergic influences on plus-maze behaviour in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperpolarization of serotonergic neurons by serotonin and LSD: studies in brain slices showing increased K+ conductance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin receptor 1A knockout: an animal model of anxiety-related disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential mechanisms involved in the anticonflict action of benzodiazepines injected into the central amygdala and mammillary body.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models of chronic anxiety and "fearlessness".

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional densities of benzodiazepine sites in the CNS of alcohol-naive P and NP rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiogenic effects of methyl-beta-carboline-3-carboxylate in a light/dark choice situation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiological assessment of the effects of antidepressant treatments on the efficacy of 5-HT neurotransmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: a pilot study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative effects of chronic 8-OH-DPAT, gepirone and ipsapirone treatment on the sensitivity of somatodendritic 5-HT1A autoreceptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress and antidepressant effects on hippocampal and cortical 5-HT1A and 5-HT2 receptors and transport sites for serotonin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single administration of 5-HT1A agonists decreases 5-HT1A presynaptic, but not postsynaptic receptor-mediated responses: relationship to antidepressant-like action

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased anxiety of mice lacking the serotonin1A receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1A receptor responsivity in anxiety disorders and depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant-like behavioral effects of serotonin receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis of the cholinergic and serotonergic modulation of GABAergic neurons in the hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAA receptor channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kindling-induced long-lasting changes in synaptic transmission in the basolateral amygdala

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic standard for competitive RT-PCR quantitation of 13 GABA receptor type A subunit mRNAs in rats and mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin receptor binding in a colony model of chronic social stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and simple chromatographic method for the determination of diazepam and its major metabolites in human plasma and urine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative RT-PCR: pitfalls and potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced benzodiazepine sensitivity in patients with panic disorder: comparison with patients with obsessive-compulsive disorder and normal subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiological effects of N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl) cyclohexane carboxamide (WAY 100635) on dorsal raphe serotonergic neurons and CA1 hippocampal pyramidal cells in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced benzodiazepine receptor binding in panic disorders measured by iomazenil SPECT

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of diazepam, pentobarbital, phenytoin and pentylenetetrazol on hippocampal paired-pulse inhibition in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonergic modulation of neurotransmission in the rat basolateral amygdala.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin modulation of sensory inputs to the lateral amygdala: dependency on corticosterone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropsychiatric disorders and the multiple human brain serotonin receptor subtypes and subsystems

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A.E. Bennett Research Award. Regulation of serotonin1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus: implications for the neurobiology of depression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10751426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.20-08-02758.2000

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772213&resulttype=core&format=json

12 May 2020

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