(Q49093581)

English

Brain net unidirectional uptake of alpha-[14c]methyl-L-tryptophan (alpha-MTrp) and its correlation with regional serotonin synthesis, tryptophan incorporation into proteins, and permeability surface area products of tryptophan and alpha-MTrp.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

Brain net unidirectional uptake of alpha-[14c]methyl-L-tryptophan (alpha-MTrp) and its correlation with regional serotonin synthesis, tryptophan incorporation into proteins, and permeability surface area products of tryptophan and alpha-MTrp. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

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author name string

M Diksic

1

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

Y Tohyama

2

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

A Takada

3

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

publication date

1 December 2000

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

Neurochemical Research

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

25

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

12

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

1537-1546

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

Determination of the lumped constant for the alpha-methyltryptophan method of estimating the rate of serotonin synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of serotonin biosynthesis in brain: role of the high affinity uptake of tryptophan into serotonergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exogenous tryptophan increases synthesis, storage, and intraneuronal metabolism of 5-hydroxytryptamine in the rat hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new method to measure brain serotonin synthesis in vivo. I. Theory and basic data for a biological model

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of protein synthesis and glucose utilization in the hypoglossal nucleus induced by axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A.E. Bennett Award Paper. A kinetic analysis of 5-hydroxyindoleacetic acid excretion from rat brain and csf

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of active transport of tryptophan in the control of 5-hydroxytryptamine biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure of decreased serotonin uptake or monoamine oxidase inhibition to block the acceleration in brain 5-hydroxyindole synthesis that follows food consumption

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin synthesis rate measured in living dog brain by positron emission tomography

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional transport of tryptophan in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of alpha-methyl-L-tryptophan in rhesus monkeys and calculation of the lumped constant for estimating the rate of serotonin synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tryptophan depletion during continuous CSF sampling in healthy human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT1A receptors in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic constants for blood-brain barrier amino acid transport in conscious rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of fluoxetine on regional serotonin synthesis in the rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha[C-11]methyl-L-tryptophan PET maps brain serotonin synthesis and kynurenine pathway metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain Serotonin Content: Physiological Regulation by Plasma Neutral Amino Acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid steady-state analysis of blood-brain transfer of L-Trp in rat, with special reference to the plasma protein binding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DL-fenfluramine increases the 5-HT synthesis rate in the terminals while decreasing it in the cell bodies of the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The involvement of serotonin in psychiatric disorders and behaviour

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of proposed determinants of brain tryptophan concentration in rats after portocaval anastomosis or sham operation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute effects of 3,4-methylenedioxymethamphetamine on brain serotonin synthesis in the dog studied by positron emission tomography

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of albumin binding and amino acid competition on tryptophan uptake into brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain metabolism: a perspective from the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Image generation of serotonin synthesis rates using alpha-methyltryptophan and PET.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human brain serotonin synthesis capacity measured in vivo with alpha-[C-11]methyl-L-tryptophan

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of steady-state kinetics to the uptake and decline of H3-NE in the rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased brain serotonin synthesis in migraine

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation of a less-invasive method for measurement of serotonin synthesis rate with alpha-[11C]methyl-tryptophan

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo and in vitro activation of soluble tryptophan hydroxylase from rat brainstem

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new method to measure brain serotonin synthesis in vivo. II. A practical autoradiographic method tested in normal and lithium-treated rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Narcotic drugs: effects on the serotonin biosynthetic systems of the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenine pathway enzymes in brain: responses to ischemic brain injury versus systemic immune activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of albumin, amino acids, and clofibrate on the uptake of tryptophan by the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is alpha-methyl-L-tryptophan a good tracer for brain serotonin synthesis measurements, and does the lumped constant vary in different structures of the rat brain?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of acute and chronic administration of the serotonin1A agonist buspirone on serotonin synthesis in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences between males and females in rates of serotonin synthesis in human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute and chronic D-fenfluramine treatments have different effects on serotonin synthesis rates in the rat brain: an autoradiographic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of MDMA (3,4-methylenedioxymethamphetamine) on the 5-HT synthesis rate in the rat brain: an autoradiographic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The suitability of [11C]-alpha-methyl-L-tryptophan as a tracer for serotonin synthesis: studies with dual administration of [11C] and [14C] labeled tracer

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How does displacement of albumin-bound tryptophan cause sustained increases in the free tryptophan concentration in plasma and 5-hydroxytryptamine synthesis in brain?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin 5HT2 receptor imaging in the human brain using positron emission tomography and a new radioligand, [18F]altanserin: results in young normal controls

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of tryptophan administration on tryptophan, 5-hydroxyindoleacetic acid and indoleacetic acid in human lumbar and cisternal cerebrospinal fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods for Quantifying the transport of drugs across brain barrier systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain serotonin synthesis rates in rhesus monkeys determined by [11C]alpha-methyl-L-tryptophan and positron emission tomography compared to CSF 5-hydroxyindole-3-acetic acid concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positron emission tomography imaging of serotonin transporters in the human brain using [11C](+)McN5652

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of [C-11]alpha-methyl-tryptophan kinetics for the estimation of serotonin synthesis rate in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Content of quinolinic acid and of other tryptophan metabolites increases in brain regions of rats used as experimental models of hepatic encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and autoradiographic measurements of brain serotonin synthesis rate in the freely moving rat: a reexamination of the alpha-methyl-L-tryptophan method

1 reference

https://pubmed.ncbi.nlm.nih.gov/11152382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1026654116999

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 February 2018

http://europepmc.org/abstract/MED/11152382

ResearchGate publication ID

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