(Q49222747)

19 February 2018

title

Prospects for antidepressant drug discovery. (English)

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19 February 2018

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Holsboer F

1

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19 February 2018

publication date

1 July 2001

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19 February 2018

published in

Biological Psychology

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19 February 2018

volume

57

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19 February 2018

issue

1-3

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19 February 2018

page(s)

47-65

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19 February 2018

Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress.

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Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2.

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Depression and the course of coronary artery disease

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The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders.

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Pituitary-adrenal-system regulation and psychopathology during amitriptyline treatment in elderly depressed patients and normal comparison subjects

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The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety

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7 January 2021

The corticosteroid receptor hypothesis of depression

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7 January 2021

Altered hypothalamic-pituitary-adrenocortical regulation in healthy subjects at high familial risk for affective disorders

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7 January 2021

Sleep deprivation and bright light as potential augmenters of antidepressant drug treatment--neurobiological and psychometric assessment of course.

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Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning

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7 January 2021

The anxiolytic effect of the CRH(1) receptor antagonist R121919 depends on innate emotionality in rats.

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7 January 2021

Hyperactivity of CRH neuronal circuits as a target for therapeutic interventions in affective disorders

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7 January 2021

Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey

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7 January 2021

Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2.

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7 January 2021

Chronic infusion of a CRH1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats

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7 January 2021

Behavioural profiles of two Wistar rat lines selectively bred for high or low anxiety-related behaviour.

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7 January 2021

Differential behavioural effects of chronic infusion of CRH 1 and CRH 2 receptor antisense oligonucleotides into the rat brain.

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7 January 2021

Long-term intracerebroventricular infusion of corticotropin-releasing hormone alters neuroendocrine, neurochemical, autonomic, behavioral, and cytokine responses to a systemic inflammatory challenge.

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7 January 2021

Corticosteroid receptor function is decreased in depressed patients

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7 January 2021

Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study

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7 January 2021

Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression.

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7 January 2021

Validity of clinical trials of antidepressants

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7 January 2021

Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients

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7 January 2021

Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system.

1 reference

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7 January 2021

Hypothalamic-pituitary-adrenocortical axis changes in the rat after long-term treatment with the reversible monoamine oxidase-A inhibitor moclobemide

1 reference

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7 January 2021

The dexamethasone/corticotropin-releasing hormone test in depression in bipolar and unipolar affective illness.

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7 January 2021

Health care costs associated with depressive and anxiety disorders in primary care.

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7 January 2021

Corticotropin-releasing hormone (CRH) antisense oligodeoxynucleotide induces anxiolytic effects in rat

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

Corticotropin-releasing hormone receptor (type I) antisense targeting reduces anxiety.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

Corticotropin-releasing hormone receptor subtypes and emotion

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https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior.

1 reference

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7 January 2021

cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

Current issues in the economics of depression management

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

Cortisol response to a combined dexamethasone-human corticotrophin-releasing hormone challenge in patients with depression

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

Prediction of medium-term outcome by cortisol response to the combined dexamethasone-CRH test in patients with remitted depression

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0511%2801%2900089-8

7 January 2021

10.1016/S0301-0511(01)00089-8

Identifiers

DOI

1 reference

19 February 2018

PubMed ID

11454434

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19 February 2018