(Q49259151)

19 February 2018

title

Tribbles Pseudokinase 3 Induces Both Apoptosis and Autophagy in Amyloid-β-induced Neuronal Death. (English)

1 reference

19 February 2018

1 reference

Suraiya Saleem

1

1 reference

19 February 2018

Subhas Chandra Biswas

series ordinal

2

1 reference

19 February 2018

language of work or name

English

0 references

publication date

23 December 2016

1 reference

19 February 2018

Journal of Biological Chemistry

published in

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19 February 2018

volume

292

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19 February 2018

issue

7

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19 February 2018

page(s)

2571-2585

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19 February 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5314157/fullTextXML

inferred from PubMed Central ID database lookup

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Sublethal doses of β-amyloid peptide abrogate DNA-dependent protein kinase activity

22 May 2018

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Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response.

22 May 2018

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Inhibition of β-amyloid1-42 internalization attenuates neuronal death by stabilizing the endosomal-lysosomal system in rat cortical cultured neurons

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22 May 2018

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The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.

22 May 2018

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Autophagy in Alzheimer's disease

22 May 2018

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Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

22 May 2018

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22 May 2018

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22 May 2018

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Ultrastructural evidence of amyloid beta-induced autophagy in PC12 cells

22 May 2018

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FoxO transcription factors promote autophagy in cardiomyocytes

22 May 2018

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Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

22 May 2018

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22 May 2018

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Autophagy protects neuron from Abeta-induced cytotoxicity

22 May 2018

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Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis

22 May 2018

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Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila

22 May 2018

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The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

The molecular mechanism of endoplasmic reticulum stress-induced apoptosis in PC-12 neuronal cells: the protective effect of insulin-like growth factor I.

22 May 2018

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Neuronal apoptosis and autophagy cross talk in aging PS/APP mice, a model of Alzheimer's disease

22 May 2018

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Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

22 May 2018

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TRB3 suppresses adipocyte differentiation by negatively regulating PPARgamma transcriptional activity

22 May 2018

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FoxO3 controls autophagy in skeletal muscle in vivo

22 May 2018

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TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4.

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

Intracellular amyloid-beta in Alzheimer's disease

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

22 May 2018

Amyloid-beta aggregation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

Emerging roles of pseudokinases

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

Tribbles: novel regulators of cell function; evolutionary aspects

22 May 2018

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Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation

22 May 2018

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Genotoxic and endoplasmic reticulum stresses differentially regulate TRB3 expression

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

Bim is a direct target of a neuronal E2F-dependent apoptotic pathway.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

22 May 2018

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Human tribbles, a protein family controlling mitogen-activated protein kinase cascades

22 May 2018

1 reference

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First evidence for helical transitions in supercoiled DNA by amyloid Beta Peptide (1-42) and aluminum: a new insight in understanding Alzheimer's disease.

22 May 2018

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JASPAR: an open-access database for eukaryotic transcription factor binding profiles

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5314157

Identification of patterns in biological sequences at the ALGGEN server: PROMO and MALGEN.

22 May 2018

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TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

22 May 2018

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SINK Is a p65-interacting Negative Regulator of NF-κB-dependent Transcription

22 May 2018

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Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

22 May 2018

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Alzheimer's disease: genes, proteins, and therapy

22 May 2018

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Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

22 May 2018

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Effects of injected Alzheimer beta-amyloid cores in rat brain.

22 May 2018

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

22 May 2018

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Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system.

22 May 2018

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TRB3 interacts with SMAD3 promoting tumor cell migration and invasion.

14 August 2018

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TRB3 overexpression due to endoplasmic reticulum stress inhibits AKT kinase activation of tongue squamous cell carcinoma.

14 August 2018

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TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action

14 August 2018

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Amyloid-beta interrupts the PI3K-Akt-mTOR signaling pathway that could be involved in brain-derived neurotrophic factor-induced Arc expression in rat cortical neurons

14 August 2018

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Monitoring autophagic degradation of p62/SQSTM1.

14 August 2018

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Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.

14 August 2018

1 reference

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Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease

14 August 2018

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FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

14 August 2018

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The neuropeptide PACAP attenuates beta-amyloid (1-42)-induced toxicity in PC12 cells

14 August 2018

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Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: possible role in tangle formation.

14 August 2018

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Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways

14 August 2018

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Crossref

https://api.crossref.org/works/10.1074%2FJBC.M116.744730

Phosphoinositide-3-Kinase Activation Controls Synaptogenesis and Spinogenesis in Hippocampal Neurons

21 January 2018

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12 December 2020

From worm to human: bioinformatics approaches to identify FOXO target genes

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Autophagy is activated by apoptotic signalling in sympathetic neurons: an alternative mechanism of death execution

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12 December 2020

Caspase-2 mediates neuronal cell death induced by beta-amyloid

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12 December 2020

The neuronal endosomal-lysosomal system in Alzheimer's disease

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12 December 2020

Identifiers

DOI

10.1074/JBC.M116.744730

1 reference

19 February 2018

PMCID

5314157

1 reference

19 February 2018

PubMed ID

28011637

1 reference

19 February 2018