(Q50074942)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429900%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

title

N-Acetyl Cysteine Functions as a Fast-Acting Antioxidant by Triggering Intracellular H2S and Sulfane Sulfur Production (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429900%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

author name string

Daria Ezeriņa

1

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15 March 2020

Yoko Takano

2

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15 March 2020

Kenjiro Hanaoka

3

1 reference

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15 March 2020

Yasuteru Urano

4

1 reference

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15 March 2020

Tobias P Dick

5

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15 March 2020

publication date

8 February 2018

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15 March 2020

published in

Cell chemical biology

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15 March 2020

volume

25

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15 March 2020

issue

4

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15 March 2020

page(s)

447-459.e4

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The effect of three alpha-keto acids on 3-mercaptopyruvate sulfurtransferase activity

15 March 2020

cites work

1 reference

12 December 2020

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

1 reference

12 December 2020

Acylase I-catalyzed deacetylation of N-acetyl-L-cysteine and S-alkyl-N-acetyl-L-cysteines.

1 reference

12 December 2020

Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide

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12 December 2020

The reaction of superoxide radical with N-acetylcysteine

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12 December 2020

Hydrogen sulfide protects neurons from oxidative stress

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12 December 2020

Supplementation with N-acetylcysteine and taurine failed to restore glutathione content in liver of streptozotocin-induced diabetics rats but protected from oxidative stress.

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12 December 2020

Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

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12 December 2020

Induction of reactive oxygen intermediates-dependent programmed cell death in human malignant ex vivo glioma cells and inhibition of the vascular endothelial growth factor production by taurolidine

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12 December 2020

Mammalian cysteine metabolism: new insights into regulation of cysteine metabolism

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12 December 2020

Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method

1 reference

12 December 2020

Kinetics of uptake and deacetylation of N-acetylcysteine by human erythrocytes

1 reference

12 December 2020

Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels

1 reference

12 December 2020

Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S

1 reference

12 December 2020

Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma

1 reference

12 December 2020

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

1 reference

12 December 2020

Proximity-based protein thiol oxidation by H2O2-scavenging peroxidases

1 reference

12 December 2020

Thiol redox transitions in cell signaling: a lesson from N-acetylcysteine.

1 reference

12 December 2020

PLP-dependent H(2)S biogenesis

1 reference

12 December 2020

Development of a highly selective fluorescence probe for hydrogen sulfide

1 reference

12 December 2020

The reaction of H(2)S with oxidized thiols: generation of persulfides and implications to H(2)S biology.

1 reference

12 December 2020

In vivo mapping of hydrogen peroxide and oxidized glutathione reveals chemical and regional specificity of redox homeostasis.

1 reference

12 December 2020

The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.

1 reference

12 December 2020

Hydrogen sulfide protects HUVECs against hydrogen peroxide induced mitochondrial dysfunction and oxidative stress

1 reference

12 December 2020

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE).

1 reference

12 December 2020

Cystathionine gamma-lyase expression is regulated by exogenous hydrogen peroxide in the mammalian cells.

1 reference

12 December 2020

The chemistry and biological activities of N-acetylcysteine

1 reference

12 December 2020

Polysulfides link H2S to protein thiol oxidation.

1 reference

12 December 2020

Oral and Intravenous Acetylcysteine for Treatment of Acetaminophen Toxicity: A Systematic Review and Meta-analysis

1 reference

12 December 2020

Preparation and use of MitoPY1 for imaging hydrogen peroxide in mitochondria of live cells

1 reference

12 December 2020

Chemical aspects of hydrogen sulfide measurements in physiological samples

1 reference

12 December 2020

Antioxidants accelerate lung cancer progression in mice

1 reference

12 December 2020

Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling

1 reference

12 December 2020

β-Lapachone induces programmed necrosis through the RIP1-PARP-AIF-dependent pathway in human hepatocellular carcinoma SK-Hep1 cells

1 reference

12 December 2020

Sulfur as a signaling nutrient through hydrogen sulfide

1 reference

12 December 2020

Organization of the human mitochondrial hydrogen sulfide oxidation pathway

1 reference

12 December 2020

Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: implications of their possible biological activity and utility

1 reference

12 December 2020

Characterization and interaction studies of two isoforms of the dual localized 3-mercaptopyruvate sulfurtransferase TUM1 from humans

1 reference

12 December 2020

Protective effects of N-acetylcysteine on cisplatin-induced oxidative stress and DNA damage in HepG2 cells

1 reference

12 December 2020

Kinetic and thermodynamic studies on the disulfide-bond reducing potential of hydrogen sulfide

1 reference

12 December 2020

Endogenous hydrogen sulfide production is essential for dietary restriction benefits

1 reference

12 December 2020

Real-time assays for monitoring the influence of sulfide and sulfane sulfur species on protein thiol redox states

1 reference

12 December 2020

Mediation of exogenous hydrogen sulfide in recovery of ischemic post-conditioning-induced cardioprotection via down-regulating oxidative stress and up-regulating PI3K/Akt/GSK-3β pathway in isolated aging rat hearts

1 reference

12 December 2020

Intravenous Administration of Stable-Labeled N-Acetylcysteine Demonstrates an Indirect Mechanism for Boosting Glutathione and Improving Redox Status.

1 reference

12 December 2020

Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

1 reference

12 December 2020

Reaction of Hydrogen Sulfide with Disulfide and Sulfenic Acid to Form the Strongly Nucleophilic Persulfide.

1 reference

12 December 2020

Diallyl Trisulfide Is a Fast H2S Donor, but Diallyl Disulfide Is a Slow One: The Reaction Pathways and Intermediates of Glutathione with Polysulfides.

1 reference

12 December 2020

Antioxidants can increase melanoma metastasis in mice

1 reference

12 December 2020

Oxidative stress inhibits distant metastasis by human melanoma cells

1 reference

12 December 2020

AP39, A Mitochondrially Targeted Hydrogen Sulfide Donor, Exerts Protective Effects in Renal Epithelial Cells Subjected to Oxidative Stress in Vitro and in Acute Renal Injury in Vivo

1 reference

12 December 2020

Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response

1 reference

12 December 2020

A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems.

1 reference

12 December 2020

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

1 reference

12 December 2020

Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation.

1 reference

12 December 2020

The chemical biology of protein hydropersulfides: Studies of a possible protective function of biological hydropersulfide generation.

1 reference

12 December 2020

Quantitative Persulfide Site Identification (qPerS-SID) Reveals Protein Targets of H2S Releasing Donors in Mammalian Cells

1 reference

12 December 2020

The chemical biology of the persulfide (RSSH)/perthiyl (RSS·) redox couple and possible role in biological redox signaling

1 reference

12 December 2020

Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application.

1 reference

12 December 2020

Synthesis of l-cysteine derivatives containing stable sulfur isotopes and application of this synthesis to reactive sulfur metabolome

1 reference

12 December 2020

Systematic in vitro assessment of responses of roGFP2-based probes to physiologically relevant oxidant species

1 reference

12 December 2020

H2S oxidation by nanodisc-embedded human sulfide quinone oxidoreductase

1 reference

12 December 2020

Polysulfide-1-oxides react with peroxyl radicals as quickly as hindered phenolic antioxidants and do so by a surprising concerted homolytic substitution.

1 reference

12 December 2020

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics.

1 reference

12 December 2020

Chemical Biology of H2S Signaling through Persulfidation

1 reference

12 December 2020

10.1016/J.CHEMBIOL.2018.01.011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429900%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429900%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

PubMed publication ID

29429900

1 reference