(Q50115192)

25 February 2018

title

Mutagens that are not carcinogens: faulty theory or faulty tests? (English)

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25 February 2018

author name string

Zeiger E

series ordinal

1

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25 February 2018

language of work or name

English

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publication date

1 May 2001

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25 February 2018

published in

Mutation Research

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25 February 2018

volume

492

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25 February 2018

issue

1-2

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25 February 2018

page(s)

29-38

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25 February 2018

Revised methods for the Salmonella mutagenicity test

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Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals

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An evaluation of 6 short-term tests for detecting organic chemical carcinogens

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Identification of rodent carcinogens and noncarcinogens using genetic toxicity tests: premises, promises, and performance.

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7 January 2021

Chemicals showing no evidence of carcinogenicity in long-term, two-species rodent studies: the need for short-term test data

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Significance of the genotoxic activities observed in vitro for 35 of 70 NTP noncarcinogens.

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Reevaluation of the mutagenicity and carcinogenicity of chemicals previously identified as "false positives" in the Salmonella typhimurium mutagenicity assay

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Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals.

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7 January 2021

An overview of prechronic and chronic toxicity/carcinogenicity experimental study designs and criteria used by the National Toxicology Program

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Chemicals mutagenic in Salmonella typhimurium strain TA1535 but not in TA100.

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Fundamental structural alerts to potential carcinogenicity or noncarcinogenicity

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Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP

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7 January 2021

Studies on the mutagenicity of p-phenylenediamine in Salmonella typhimurium. Presence of PCB's in rat-liver microsomal fraction induced by Aroclor

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The effect of dimethylsulfoxide on the mutagenicity of the hair dye p-phenylenediamine.

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Reproducibility of microbial mutagenicity assays: II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escherichia coli

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Failure of short-term in vitro mutagenicity tests to predict the animal carcinogenicity of hair dyes.

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Structure-activity relationship within a series of m-diaminobenzene derivatives

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7 January 2021

Correlation of hepatocellular proliferation with hepatocarcinogenicity induced by the mutagenic noncarcinogen:carcinogen pair--2,6- and 2,4-diaminotoluene.

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Distinction of mutagenic carcinogens from a mutagenic noncarcinogen in the big blue transgenic mouse

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Differential in vivo mutagenicity of the carcinogen/non-carcinogen pair 2,4- and 2,6-diaminotoluene

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Isolation of the mutagenic and DNA adduct-inducing components from a commercial preparation of HC blue 1 using Salmonella (TA98) bioassay-directed HPLC fractionation.

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Comparative mutagenicity of aliphatic epoxides in Salmonella.

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Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. III. Results with 27 chemicals.

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7 January 2021

Responses of the L5178Y mouse lymphoma forward mutation assay: V. Gases and vapors

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7 January 2021

Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: confirmation of earlier results with 41 additional chemicals

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7 January 2021

Mutagenicity of 42 chemicals in Salmonella.

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Comparative characterization of CHCl(3) metabolism and toxicokinetics in rodent strains differently susceptible to chloroform-induced carcinogenicity

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7 January 2021

Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays.

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Analysis of the National Toxicology Program data on in vitro genetic toxicity tests using multivariate statistical methods

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Predictive strategies for selecting 379 NCI/NTP chemicals evaluated for carcinogenic potential: scientific and public health impact

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Identifiers

DOI

1 reference

25 February 2018

1 reference

25 February 2018