(Q50198817)

English

Different mutational profiles induced by N-nitroso-N-ethylurea: effects of dose and error-prone DNA repair and correlations with DNA adducts.

scientific article published in January 1988

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scholarly article

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22 September 2019

Different mutational profiles induced by N-nitroso-N-ethylurea: effects of dose and error-prone DNA repair and correlations with DNA adducts (English)

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Europe PubMed Central

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22 September 2019

Joseph Guttenplan

3

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22 September 2019

author name string

Zielenska M

1

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22 September 2019

Beranek D

2

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22 September 2019

publication date

1 January 1988

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22 September 2019

Environmental and Molecular Mutagenesis

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22 September 2019

11

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22 September 2019

4

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22 September 2019

473-485

1 reference

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22 September 2019

DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by

1 reference

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Validation and comparative studies on 180 chemicals with S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolizing systems

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Correlation between specific DNA-methylation products and mutation induction at the HGPRT locus in Chinese hamster ovary cells.

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N-nitrosamines: bacterial mutagenesis and in vitro metabolism

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Synthesis and properties of O6-methyldeoxyguanylic acid and its copolymers with deoxycytidylic acid

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A comprehensive quantitative analysis of methylated and ethylated DNA using high pressure liquid chromatography.

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The in vivo mutagenic frequency and specificity of O6-methylguanine in phi X174 replicative form DNA.

1 reference

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Influence of neighbouring base sequence on N-methyl-N'-nitro-N-nitrosoguanidine mutagenesis in the lacI gene of Escherichia coli.

1 reference

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Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coli

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Formation and stability of alkylated pyrimidines and purines (including imidazole ring-opened 7-alkylguanine) and alkylphosphotriesters in liver DNA of adult rats treated with ethylnitrosourea or dimethylnitrosamine

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Induction kinetics of mutations at two genetic loci, DNA damage and repair in CHO cells after different exposure times to N-ethyl-N-nitrosourea

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Comparative rates of spontaneous mutation.

1 reference

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7 January 2021

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Induction of transversion mutations in Escherichia coli by N-methyl-N'-nitro-N-nitrosoguanidine is SOS dependent

1 reference

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Persistence of O 6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by Ethylnitrosourea

1 reference

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Mutagenesis and O6-ethylguanine levels in DNA from N-nitroso-N-ethylurea-treated Salmonella typhimurium: evidence for a high mutational efficiency of O6-ethylguanine.

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Target sequences for mutagenesis in Salmonella histidine-requiring mutants.

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Induction of mutations and sister-chromatid exchanges in Chinese hamster ovary cells by ethylating agents

1 reference

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Evidence for a major premutagenic ethyldeoxythymidine-DNA adduct in an in vivo system: N-nitroso-N-ethylurea-treated Salmonella typhimurium.

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7 January 2021

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Classifying mutagens as to their specificity in causing the six possible transitions and transversions: a simple analysis using the Salmonella mutagenicity assay.

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Spontaneous and mutagen-induced deletions: mechanistic studies in Salmonella tester strain TA102

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7 January 2021

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In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome

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7 January 2021

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Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents.

1 reference

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7 January 2021

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Identification of plasmid (pKM101)-coded proteins involved in mutagenesis and UV resistance

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7 January 2021

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Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis

1 reference

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7 January 2021

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DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea

1 reference

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7 January 2021

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In vitro miscoding of alkylthymines with DNA and RNA polymerases

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7 January 2021

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Assessment of mutagenic efficiency of two carcinogen-modified nucleosides, 1,N6-ethenodeoxyadenosine and O4-methyldeoxythymidine, using polymerases of varying fidelity

1 reference

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Chemical mutagenesis

1 reference

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7 January 2021

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Tissue-dependent enzyme-mediated repair or removal of O-ethyl pyrimidines and ethyl purines in carcinogen-treated rats

1 reference

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7 January 2021

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O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine

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Identifiers

10.1002/EM.2850110408

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3286248%20AND%20SRC:MED&resulttype=core&format=json

22 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3286248%20AND%20SRC:MED&resulttype=core&format=json

22 September 2019

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