(Q50255841)

English

GRB2:GAB1 [cytosol]

An instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-179849)

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Statements

protein complex

1 reference

8 July 2022

BDNF,NTF4:p-5Y-NTRK2:GRB2:GAB1:PIK3CA:PIK3R1 [plasma membrane]

1 reference

8 July 2022

GAB1 binds phosphatidylinositol-3,4,5-trisphosphate

1 reference

8 July 2022

GRB2:GAB1:PIK3R1 [cytosol]

1 reference

8 July 2022

Binding of GRB2:GAB1 to p-ERBB2:p-EGFR

1 reference

8 July 2022

Activated NTRK2 recruits PI3K

1 reference

8 July 2022

p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]

1 reference

8 July 2022

p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]

1 reference

8 July 2022

Binding of GRB2 to GAB1

1 reference

8 July 2022

Binding of PIK3 regulatory alpha subunit to GRB2:GAB1

1 reference

8 July 2022

Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind GRB2:GAB1

1 reference

8 July 2022

Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind GRB2:GAB1

1 reference

8 July 2022

GRB2:GAB1:PIP3 [plasma membrane]

1 reference

8 July 2022

Binding of GRB2:GAB1 complex to ligand-responsive p-6Y-EGFR mutants

1 reference

8 July 2022

Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1 [plasma membrane]

1 reference

8 July 2022

p-5Y-EGFRvIII:GRB2:GAB1 [plasma membrane]

1 reference

8 July 2022

EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane]

1 reference

8 July 2022

GRB2:GAB1,GRB2:GAB1:PIP3 [cytosol]

1 reference

8 July 2022

Binding of GRB2:GAB1 complex to p-EGFRvIII mutant

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-179849

1 reference

8 July 2022

Growth factor receptor bound protein 2

1

1 reference

8 July 2022

GRB2 associated binding protein 1

1

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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