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English
Binding of GRB2:GAB1 to p-ERBB2:p-EGFR
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1306963)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1306963
part of
PI3K events in ERBB2 signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1306963
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1306963
exact match
https://identifiers.org/reactome:R-HSA-1306963
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1306963
has part(s)
GRB2:GAB1 [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1306963
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1306963
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1306963
cites work
Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1306963
Identifiers
Reactome ID
R-HSA-1306963
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1306963
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