(Q50259013)

English

activated thrombin (factor IIa) [extracellular region]

An instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-156786)

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2 references

8 July 2022

8 July 2022

https://www.ebi.ac.uk/complexportal/complex/CPX-6222

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factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst)

1 reference

8 July 2022

GP1b-IX-V complex:activated thrombin (factor IIa) [plasma membrane]

1 reference

8 July 2022

Thrombin:Proteinase-activated receptors [plasma membrane]

1 reference

8 July 2022

Factor IIa inhibitors (compounds) binds IIa

1 reference

8 July 2022

factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer

1 reference

8 July 2022

Activated thrombin (factor IIa) cleaves PAR3,4, activating them

1 reference

8 July 2022

Factor IIa inhibitors (peptide) binds IIa

1 reference

8 July 2022

Factor IIa inhibitors (peptide):IIa [extracellular region]

1 reference

8 July 2022

activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin

1 reference

8 July 2022

activated thrombin (factor IIa):SERPIND1 [extracellular region]

1 reference

8 July 2022

thrombin:cleaved SERPINC1 [extracellular region]

1 reference

8 July 2022

factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides

1 reference

8 July 2022

Cleavage of factor XII variant by activated thrombin

1 reference

8 July 2022

activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin

1 reference

8 July 2022

factor V -> factor Va + factor V activation peptide

1 reference

8 July 2022

Proteinase-activated receptors can bind thrombin

1 reference

8 July 2022

Factor IIa inhibitors (compounds):IIa [extracellular region]

1 reference

8 July 2022

Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)

1 reference

8 July 2022

Thrombin proteolyzes IGF:IGFBP3:ALS

1 reference

8 July 2022

F8 variant is not cleaved by thrombin

1 reference

8 July 2022

prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst)

1 reference

8 July 2022

Ligands of GPCRs that activate Gq/11 [extracellular region]

1 reference

8 July 2022

Thrombin binding to GP1b:IX:V

1 reference

8 July 2022

prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)

1 reference

8 July 2022

fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B

1 reference

8 July 2022

Activated thrombin, (ELANE) [extracellular region]

1 reference

8 July 2022

Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-156786

1 reference

8 July 2022

Coagulation factor II, thrombin

quantity

1

1 reference

8 July 2022

6

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q50259013)

activated thrombin (factor IIa) [extracellular region]

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