(Q50284446)

1 March 2018

title

Anticoagulant activity of a sulfated galactan: serpin-independent effect and specific interaction with factor Xa. (English)

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1 March 2018

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Bianca F Glauser

1

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1 March 2018

Ricardo M Rezende

2

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1 March 2018

Fabio R Melo

3

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1 March 2018

Mariana S Pereira

4

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1 March 2018

Ivo M B Francischetti

5

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1 March 2018

Robson Q Monteiro

6

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1 March 2018

Alireza R Rezaie

7

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1 March 2018

Paulo A S Mourão

8

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1 March 2018

publication date

1 December 2009

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1 March 2018

Thrombosis and Haemostasis

published in

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1 March 2018

volume

102

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1 March 2018

issue

6

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1 March 2018

page(s)

1183-1193

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1 March 2018

Outbreak of adverse reactions associated with contaminated heparin

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Contaminated heparin associated with adverse clinical events and activation of the contact system

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Sulfation patterns of glycosaminoglycans encode molecular recognition and activity

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Ixolaris: a factor Xa heparin-binding exosite inhibitor

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Searching for alternatives to heparin: sulfated fucans from marine invertebrates

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Molecular mapping of the heparin-binding exosite of thrombin

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Structure-function relationships of epidermal growth factor modules in vitamin K-dependent clotting factors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

A novel one-step purification of human α-thrombin after direct activation of crude prothrombin enriched from plasma

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery: a meta-analysis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Low molecular weight heparin in prevention of perioperative thrombosis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Antithrombotic properties of Ixolaris, a potent inhibitor of the extrinsic pathway of the coagulation cascade.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

An algal sulfated galactan has an unusual dual effect on venous thrombosis due to activation of factor XII and inhibition of the coagulation proteases

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Profiling the sulfation specificities of glycosaminoglycan interactions with growth factors and chemotactic proteins using microarrays

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Antithrombin-mediated anticoagulant activity of sulfated polysaccharides: different mechanisms for heparin and sulfated galactans

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Bothrojaracin, a proexosite I ligand, inhibits factor Va-accelerated prothrombin activation.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Hypersulfated low molecular weight heparin with reduced affinity for antithrombin acts as an anticoagulant by inhibiting intrinsic tenase and prothrombinase

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Calcium enhances heparin catalysis of the antithrombin-factor Xa reaction by a template mechanism. Evidence that calcium alleviates Gla domain antagonism of heparin binding to factor Xa.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Structure and Anticoagulant Activity of Sulfated Galactans

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791905

Identification of basic residues in the heparin-binding exosite of factor Xa critical for heparin and factor Va binding

30 November 2018

1 reference

12 December 2020

Heparins in the new millennium: will unfractionated heparin survive? Epilogue

1 reference

12 December 2020

Heparin-binding exosite of factor Xa

1 reference

12 December 2020

Dual effects of sulfated D-galactans from the red algae Botryocladia occidentalis preventing thrombosis and inducing platelet aggregation

1 reference

12 December 2020

Is there a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans?

1 reference

12 December 2020

A 2-sulfated, 3-linked α-l-galactan is an anticoagulant polysaccharide

1 reference

12 December 2020

Respective role of antithrombin III and heparin cofactor II in the in vitro anticoagulant effect of heparin and of various sulphated polysaccharides

1 reference

12 December 2020

The mode of action of heparin in plasma

1 reference

12 December 2020

Effects of gamma-carboxyglutamic acid and epidermal growth factor-like modules of factor IX on factor X activation. Studies using proteolytic fragments of bovine factor IX

1 reference

12 December 2020

Inhibition by heparin of the human blood coagulation intrinsic pathway factor X activator

1 reference

12 December 2020

Depolymerized holothurian glycosaminoglycan with novel anticoagulant actions: antithrombin III- and heparin cofactor II-independent inhibition of factor X activation by factor IXa-factor VIIIa complex and heparin cofactor II-dependent inhibition of

1 reference

12 December 2020

Structure and anticoagulant activity of sulfated fucans. Comparison between the regular, repetitive, and linear fucans from echinoderms with the more heterogeneous and branched polymers from brown algae

1 reference

12 December 2020

Sulfated galactan is a catalyst of antithrombin-mediated inactivation of alpha-thrombin

1 reference

12 December 2020

Serpin-independent anticoagulant activity of a fucosylated chondroitin sulfate

1 reference

12 December 2020

Identifiers

DOI

10.1160/TH09-04-0273

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1 March 2018

PMC publication ID

2791905

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1 March 2018

PubMed publication ID

19967150

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1 March 2018