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RRM2 gene expression is stimulated by E2F1 and inhibited by E2F6
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8961982)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
part of
Transcriptional Regulation by E2F6
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
G1/S-Specific Transcription
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
exact match
https://identifiers.org/reactome:R-HSA-8961982
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
has part(s)
Ribonucleotide reductase regulatory subunit M2
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
E2F1:TFDP1,TFDP2:RRM2 gene [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
E2F6:(TFDP1,TFDP2):RRM2 gene [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
cites work
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
Combinatorial gene control involving E2F and E Box family members
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
Identifiers
Reactome ID
R-HSA-8961982
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8961982
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