(Q50287801)

English

p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8854905)

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Statements

biological process

1 reference

8 July 2022

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-8854905

1 reference

8 July 2022

2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane]

1

object has role

1 reference

8 July 2022

p85-containing Class 1A PI3Ks [cytosol]

1

object has role

1 reference

8 July 2022

2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane]

1

object has role

1 reference

8 July 2022

Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.

1 reference

8 July 2022

Enhanced phosphatidylinositol 3-kinase activity and high phosphorylation state of its downstream signalling molecules mediated by ret with the MEN 2B mutation

1 reference

8 July 2022

Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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