(Q40854118)

English

Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.

scientific article published on December 2000

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995764%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995764%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

protein-protein interaction

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based on heuristic

inferred from title

Rizaldy P Scott

2

1 reference

Europe PubMed Central

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10 November 2019

author name string

V Besset

1

1 reference

Europe PubMed Central

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10 November 2019

C F Ibáñez

3

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10 November 2019

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publication date

1 December 2000

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10 November 2019

Journal of Biological Chemistry

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10 November 2019

275

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10 November 2019

39159-39166

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10 November 2019

50

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10 November 2019

Regulation of cell fate decision of undifferentiated spermatogonia by GDNF.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Functional receptor for GDNF encoded by the c-ret proto-oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

GDNF signalling through the Ret receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Characterization of a multicomponent receptor for GDNF.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

GDNF family neurotrophic factor signaling: four masters, one servant?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

The GDNF family ligands and receptors - implications for neural development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

GDNF triggers a novel ret-independent Src kinase family-coupled signaling via a GPI-linked GDNF receptor alpha1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

RET in human development and oncogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Molecular mechanisms of RET activation in human neoplasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Grb2 binding to the different isoforms of Ret tyrosine kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Ligand stimulation of a Ret chimeric receptor carrying the activating mutation responsible for the multiple endocrine neoplasia type 2B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Identification of Shc docking site on Ret tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Characterization of Ret-Shc-Grb2 complex induced by GDNF, MEN 2A, and MEN 2B mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Shc and Enigma are both required for mitogenic signaling by Ret/ptc2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Enhanced phosphatidylinositol 3-kinase activity and high phosphorylation state of its downstream signalling molecules mediated by ret with the MEN 2B mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Cell cycle-dependent activation of Ras.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Structure and function of phosphoinositide 3-kinases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Renal agenesis and the absence of enteric neurons in mice lacking GDNF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Renal and neuronal abnormalities in mice lacking GDNF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Defects in enteric innervation and kidney development in mice lacking GDNF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

The multiple endocrine neoplasia type 2B point mutation switches the specificity of the Ret tyrosine kinase towards cellular substrates that are susceptible to interact with Crk and Nck

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006908200

21 January 2018

Identifiers

10.1074/JBC.M006908200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995764%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995764%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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