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Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
title
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses
(English)
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
main subject
Growth factor receptor bound protein 2-associated protein 1
1 reference
stated in
GOA release 2020-03-11
Growth factor receptor bound protein 2
1 reference
stated in
GOA release 2020-03-11
author name string
U. Schaeper
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
N. H. Gehring
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
K. P. Fuchs
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
M. Sachs
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
B. Kempkes
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
W. Birchmeier
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
language of work or name
English
0 references
publication date
26 June 2000
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
published in
Journal of Cell Biology
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
volume
149
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
page(s)
1419–1432
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
issue
7
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
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Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL
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Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras
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Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells
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19 March 2017
Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud
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Grb2/Ash binds directly to tyrosines 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells
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19 March 2017
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29 September 2017
The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor.
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29 September 2017
Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion
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29 September 2017
Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway
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29 September 2017
Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase
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29 September 2017
Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.
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29 September 2017
Guanine-nucleotide exchange protein C3G activates JNK1 by a ras-independent mechanism. JNK1 activation inhibited by kinase negative forms of MLK3 and DLK mixed lineage kinases
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29 September 2017
Structural determinants of SHP-2 function and specificity in Xenopus mesoderm induction
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29 September 2017
Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.
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29 September 2017
Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.
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29 September 2017
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
A three-hybrid system for detecting small ligand-protein receptor interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
Motogenic and morphogenic activity of epithelial receptor tyrosine kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
A rapid and reliable DNA preparation method for screening a large number of yeast clones by polymerase chain reaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
29 September 2017
The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
2 June 2018
Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
2 June 2018
Mechanism of met oncogene activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
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2 June 2018
Role of binding proteins to IRS-1 in insulin signalling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
27 November 2018
Genetic analysis of protein kinase B (AKT) in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
27 November 2018
Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
retrieved
27 November 2018
Efficient cell transformation by the Tpr-Met oncoprotein is dependent upon tyrosine 489 in the carboxy-terminus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175135
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27 November 2018
Erythropoietin induces the tyrosine phosphorylation of GAB1 and its association with SHC, SHP2, SHIP, and phosphatidylinositol 3-kinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10871282
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Tyrosine 1356 in the carboxyl-terminal tail of the HGF/SF receptor is essential for the transduction of signals for cell motility and morphogenesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10871282
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10871282
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Shc Binding to Nerve Growth Factor Receptor Is Mediated by the Phosphotyrosine Interaction Domain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10871282
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1083/JCB.149.7.1419
0 references
PMCID
2175135
0 references
PubMed ID
10871282
1 reference
stated in
PubMed
PubMed ID
10871282
retrieved
25 January 2017
ResearchGate publication ID
236242825
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