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p-BCR-pFGFR1 binds GRB2:GAB2
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1839095)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1839095
part of
Signaling by cytosolic FGFR1 fusion mutants
1 reference
stated in
Reactome
retrieved
13 July 2022
Reactome ID
R-HSA-1839095
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1839095
exact match
https://identifiers.org/reactome:R-HSA-1839095
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1839095
has part(s)
GRB2:GAB2 [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1839095
pY177-BCR-p-FGFR1 fusion mutant dimer [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1839095
pY177-BCR1-p-FGFR1 mutant:GRB2:GAB2 [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1839095
cites work
The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1839095
Critical role for Gab2 in transformation by BCR/ABL
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1839095
Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1839095
Identifiers
Reactome ID
R-HSA-1839095
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1839095
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