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USP9X (FAM) deubiquitinates SMAD4
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-870437)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
part of
Downregulation of SMAD2/3:SMAD4 transcriptional activity
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
Ub-specific processing proteases
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
exact match
https://identifiers.org/reactome:R-HSA-870437
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
has part(s)
water
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
Ub-SMAD4:USP9X [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
SMAD family member 4
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
Ub [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
Ubiquitin specific peptidase 9 X-linked
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
Ub-SMAD4:USP9X [cytosol]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
cites work
FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
Identifiers
Reactome ID
R-HSA-870437
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-870437
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