(Q50290133)

English

NEDD4L ubiquitinates SMAD2/3

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2176502)

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Statements

biological process

1 reference

8 July 2022

Downregulation of SMAD2/3:SMAD4 transcriptional activity

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-2176502

1 reference

8 July 2022

p-T-2S-SMAD2,3:SMAD4:NEDDL4 [nucleoplasm]

1

object of statement has role

1 reference

8 July 2022

Ub [nucleoplasm]

2

object of statement has role

1 reference

8 July 2022

NEDD4 like E3 ubiquitin protein ligase

1

object of statement has role

1 reference

8 July 2022

Ub-p-T-2S-SMAD2,3:SMAD4 [nucleoplasm]

1

object of statement has role

1 reference

8 July 2022

Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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