(Q35013177)

5 August 2017

title

Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling (English)

1 reference

5 August 2017

9

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5 August 2017

Hediye Erdjument-Bromage

8

object named as

Hediye Erdjument-Bromage

0 references

Maria J Macias

object named as

Maria J Macias

7

0 references

Joan Massagué Solé

object named as

Joan Massagué

10

0 references

author name string

Sheng Gao

1

1 reference

5 August 2017

Claudio Alarcón

2

1 reference

5 August 2017

Gopal Sapkota

3

1 reference

5 August 2017

Sadia Rahman

4

1 reference

5 August 2017

Pan-Yu Chen

5

1 reference

5 August 2017

Nina Goerner

6

1 reference

5 August 2017

publication date

1 November 2009

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5 August 2017

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5 August 2017

volume

36

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5 August 2017

issue

3

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5 August 2017

page(s)

457-468

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describes a project that uses

5 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2796330/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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SMAD proteins control DROSHA-mediated microRNA maturation

8 July 2018

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Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system

8 July 2018

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8 July 2018

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Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program

8 July 2018

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Polymorphism in NEDD4L is associated with increased salt sensitivity, reduced levels of P-renin and increased levels of Nt-proANP.

8 July 2018

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Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.

8 July 2018

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Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells

8 July 2018

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8 July 2018

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Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

8 July 2018

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PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

8 July 2018

1 reference

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Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads

8 July 2018

1 reference

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Specificity and versatility in tgf-beta signaling through Smads

8 July 2018

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Minireview: regulation of epithelial Na+ channel trafficking

8 July 2018

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Association of NEDD4L ubiquitin ligase with essential hypertension

8 July 2018

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Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases

8 July 2018

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The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines

8 July 2018

1 reference

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NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor

8 July 2018

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The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

8 July 2018

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Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

8 July 2018

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8 July 2018

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The role of individual Nedd4-2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels

8 July 2018

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Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

8 July 2018

1 reference

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Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo

8 July 2018

1 reference

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Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

8 July 2018

1 reference

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Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms

8 July 2018

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Mechanisms of action of flavopiridol

8 July 2018

1 reference

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Structural basis for phosphoserine-proline recognition by group IV WW domains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

Structural basis of Smad2 recognition by the Smad anchor for receptor activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

Ubiquitin-dependent degradation of TGF-beta-activated smad2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

8 July 2018

1 reference

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Identification of a novel inhibitor of mitogen-activated protein kinase kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

Patterning of mouse embryonic stem cell-derived pan-mesoderm by Activin A/Nodal and Bmp4 signaling requires Fibroblast Growth Factor activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

Structural determinants for high-affinity binding in a Nedd4 WW3* domain-Comm PY motif complex

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

Cyclin-dependent kinases regulate the antiproliferative function of Smads

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

Nuclear exclusion of Smad2 is a mechanism leading to loss of competence

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796330

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19917253

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2009.09.043

1 reference

5 August 2017

1 reference

5 August 2017

1 reference