(Q40437388)

20 September 2017

title

Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases (English)

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20 September 2017

Anita Morén

1

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20 September 2017

Takeshi Imamura

2

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20 September 2017

Kohei Miyazono

3

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20 September 2017

Carl-Henrik Heldin

4

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20 September 2017

Aristidis Moustakas

5

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20 September 2017

language of work or name

English

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publication date

6 April 2005

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Journal of Biological Chemistry

20 September 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

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20 September 2017

volume

280

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20 September 2017

issue

23

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20 September 2017

page(s)

22115-22123

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

20 September 2017

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A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

21 January 2018

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21 January 2018

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Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

21 January 2018

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The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation

21 January 2018

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NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor

21 January 2018

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Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

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dSmurf Selectively Degrades Decapentaplegic-activated MAD, and Its Overexpression Disrupts Imaginal Disc Development

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation

21 January 2018

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Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

21 January 2018

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Nuclear factor YY1 inhibits transforming growth factor beta- and bone morphogenetic protein-induced cell differentiation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A structural basis for mutational inactivation of the tumour suppressor Smad4

21 January 2018

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21 January 2018

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Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M414027200

1 reference

20 September 2017

1 reference