(Q40781050)

23 September 2017

title

Loss of Smad4 function in pancreatic tumors: C-terminal truncation leads to decreased stability (English)

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23 September 2017

6

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23 September 2017

Maurice D

1

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23 September 2017

Pierreux CE

2

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23 September 2017

Howell M

3

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23 September 2017

Wilentz RE

4

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23 September 2017

Owen MJ

5

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23 September 2017

language of work or name

English

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publication date

11 September 2001

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Journal of Biological Chemistry

23 September 2017

number of pages

7

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based on heuristic

inferred from page(s)

published in

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23 September 2017

volume

276

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23 September 2017

issue

46

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23 September 2017

page(s)

43175-43181

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Transcriptional control by the TGF-beta/Smad signaling system

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

A transcriptional partner for MAD proteins in TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Importin beta mediates nuclear translocation of Smad 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

TGFbeta signaling in growth control, cancer, and heritable disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Genetic events and the role of TGF beta in epithelial tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Molecular analyses of the 15q and 18q SMAD genes in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Smad4 (DPC4)--a potent tumour suppressor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

A structural basis for mutational inactivation of the tumour suppressor Smad4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

XSmad2 directly activates the activin-inducible, dorsal mesoderm gene XFKH1 in Xenopus embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

The POZ domain: a conserved protein-protein interaction motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas : a new marker of DPC4 inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Distinct oligomeric states of SMAD proteins in the transforming growth factor-beta pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Smads and early developmental signaling by the TGFbeta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Signaling inputs converge on nuclear effectors in TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Smad4 and FAST-1 in the assembly of activin-responsive factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

Crystal structure of a transcriptionally active Smad4 fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105895200

21 January 2018

Identifiers

DOI

10.1074/JBC.M105895200

1 reference

release_edmhy7qmdrfpzd62zq4hptmeha

23 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/edmhy7qmdrfpzd62zq4hptmeha

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference